[罗马尼亚东北部地区不同人口结构中风疹发病率的流行病学研究]

[Epidemiologic research on rubella incidence in various demographic structures, in a north-eastern area of Romania].

作者信息

Costan Oana-Carmen, Manole Alina

机构信息

Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină, Disciplina de Asistenţa Primară a Stării de Sănătate şi Epidemiologie.

出版信息

Rev Med Chir Soc Med Nat Iasi. 2004 Oct-Dec;108(4):880-5.

PMID:16004235

Abstract

Authors presents the results of a prospective study on the evaluation of rubella incidence on years, age groups, sex and residence area, between 1996-2003. The rubella incidence recorded 156.3% per ten thousand cases in Botoşani district, and, respectively, 32.7% per ten thousand in Iaşi district, with an epidemic peak of 4895 cases (1052.5% per ten thousand) in 2003 and a predominance in a urban area, comparatively with the rural area (p < or = 0.001), as well as the age group of 0-14 years (p < 0.001). There were recorded 53.6% per ten thousand cases in males. Taking into consideration the increased incidence of rubella, both in the studied demographic structure and at the national level, as well as the fact that the etiologic agent is extremely teratogenic, the extension of the National Vaccination Programme for rubella and congenital rubella syndrome prevention is a necessity.

摘要

作者介绍了一项前瞻性研究的结果，该研究评估了1996年至2003年间不同年份、年龄组、性别和居住地区的风疹发病率。博托沙尼区记录的风疹发病率为每万例156.3%，雅西区分别为每万例32.7%，2003年出现了4895例的流行高峰（每万例1052.5%），且城市地区的发病率高于农村地区（p≤0.001），0至14岁年龄组也是如此（p<0.001）。男性记录的发病率为每万例53.6%。考虑到风疹在研究的人口结构以及国家层面的发病率均有所上升，并且风疹病原体具有极强的致畸性，因此有必要扩大国家风疹和先天性风疹综合征预防疫苗接种计划。