Kitagawa Toshiro, Fujii Takashi, Tomohiro Yasuyuki, Maeda Kouji, Kobayashi Masakazu, Kunita Eiji, Sekiguchi Yoshitaka
Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Japan.
Int J Cardiol. 2006 May 10;109(2):188-94. doi: 10.1016/j.ijcard.2005.06.012. Epub 2005 Jul 14.
The usefulness of thin-slice multi-detector computed tomography (MDCT) has been highly expected to assess the lumens of coronary artery stents. We evaluated the usefulness of 16-slice MDCT to assess the in-stent lumen after coronary artery stenting.
In 42 consecutive patients after coronary artery stenting, retrospective ECG-gated CT-angiography using 16-slice MDCT (0.5-s rotation time, 16x0.625-mm detector collimation) was performed. The qualitative assessability of the lumens of 61 coronary stents (14 different types) by MDCT and the reasons for non-assessability were investigated. Furthermore, the evaluation of in-stent restenosis in 21 assessable stents of 16 patients, including quantitative density analysis by MDCT, was performed and the results were compared with those of conventional coronary angiography (CAG).
Of 61 stents, 42 (68.9%) were assessable. The assessability of diameter > or =3.5-mm stents made of stainless steel or cobalt was high (88.6%, 31/35), that of 3.0-mm stents was low (57.9%, 11/19) and all 2.5-mm stents were non-assessable due to partial volume effects and metal artifacts of stents. The lumens of stents made of tantalum were totally obscured and the metal artifacts of Bestent2 (gold markers) and S670 were severer than others. All non-assessable stents due to banding artifact and calcification were implanted in segment #1-3 and #6, respectively. In comparison to CAG, MDCT correctly detected the 5 in-stent restenoses and identified absence of restenoses was influenced strongly by the stent strut.
Despite some limitations, 16-slice MSCT is sufficiently useful for assessment of various coronary stents in patients and can detect in-stent restenoses of assessable stents with high accuracy in comparison to CAG.
多层螺旋CT(MDCT)薄层扫描对于评估冠状动脉支架管腔的作用一直备受期待。我们评估了16层MDCT在冠状动脉支架置入术后评估支架内管腔的作用。
对42例连续的冠状动脉支架置入术后患者,采用16层MDCT(旋转时间0.5秒,探测器准直16×0.625毫米)进行回顾性心电图门控CT血管造影。研究了MDCT对61个冠状动脉支架(14种不同类型)管腔的定性可评估性及不可评估的原因。此外,对16例患者的21个可评估支架进行了支架内再狭窄评估,包括MDCT定量密度分析,并将结果与传统冠状动脉造影(CAG)结果进行比较。
61个支架中,42个(68.9%)可评估。直径≥3.5毫米的不锈钢或钴合金支架可评估性高(88.6%,31/35),3.0毫米支架可评估性低(57.9%,11/19),所有2.5毫米支架因部分容积效应和支架金属伪影而不可评估。钽制成的支架管腔完全被遮挡,Bestent2(金色标记)和S670的金属伪影比其他支架更严重。所有因束状伪影和钙化而不可评估的支架分别植入在第1-3段和第6段。与CAG相比,MDCT正确检测出5例支架内再狭窄,且支架小梁对判断无再狭窄有很大影响。
尽管存在一些局限性,但16层MSCT对于评估患者的各种冠状动脉支架仍有足够的作用,并且与CAG相比,能够高精度地检测可评估支架的支架内再狭窄。