Riddell Carolyn E, Mallon Eamonn B
Department of Biology, University of Leicester, UK.
Brain Behav Immun. 2006 Mar;20(2):135-8. doi: 10.1016/j.bbi.2005.06.008. Epub 2005 Aug 9.
It is well established in vertebrates that there are many intricate interactions between the immune system and the nervous system. Here, we present behavioural evidence indicating a link between the immune system and the nervous system in insects. We show that otherwise non-infected bumblebees whose immune systems were challenged by a non-pathogenic immunogenic elicitor (lipopolysaccharide) have reduced abilities to learn or recall a memory in a classical conditioning paradigm. There is evidence that protein is intricately involved as this immune induced reduction in memory only becomes apparent after the bees are deprived of pollen (their only protein sources).
在脊椎动物中，免疫系统和神经系统之间存在许多复杂的相互作用，这一点已得到充分证实。在此，我们提供行为学证据，表明昆虫的免疫系统和神经系统之间存在联系。我们发现，在经典条件反射范式中，原本未受感染但免疫系统受到非致病性免疫原性激发物（脂多糖）挑战的大黄蜂，其学习或回忆记忆的能力有所下降。有证据表明蛋白质与之密切相关，因为只有在蜜蜂被剥夺花粉（它们唯一的蛋白质来源）后，这种免疫诱导的记忆减退才会变得明显。
