Lusby Patricia E, Coombes Alexandra L, Wilkinson Jenny M
School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, Australia.
Arch Med Res. 2005 Sep-Oct;36(5):464-7. doi: 10.1016/j.arcmed.2005.03.038.
Renewed interest in honey for various therapeutic purposes including treatment of infected wounds has led to the search for new antibacterial honeys. In this study we have assessed the antibacterial activity of three locally produced honeys and compared them to three commercial therapeutic honeys (including Medihoney and manuka honey).
An agar dilution method was used to assess the activity of honeys against 13 bacteria and one yeast. The honeys were tested at five concentrations ranging from 0.1 to 20%.
Twelve of the 13 bacteria were inhibited by all honeys used in this study with only Serratia marcescens and the yeast Candida albicans not inhibited by the honeys. Little or no antibacterial activity was seen at honey concentrations <1%, with minimal inhibition at 5%. No honey was able to produce complete inhibition of bacterial growth. Although Medihoney and manuka had the overall best activity, the locally produced honeys had equivalent inhibitory activity for some, but not all, bacteria.
Honeys other than those commercially available as antibacterial honeys can have equivalent antibacterial activity. These newly identified antibacterial honeys may prove to be a valuable source of future therapeutic honeys.
对蜂蜜用于包括感染伤口治疗在内的各种治疗目的的兴趣再度兴起,促使人们寻找新型抗菌蜂蜜。在本研究中,我们评估了三种本地生产的蜂蜜的抗菌活性,并将它们与三种商业治疗用蜂蜜(包括麦卢卡蜂蜜和医用蜂蜜)进行了比较。
采用琼脂稀释法评估蜂蜜对13种细菌和1种酵母菌的活性。在0.1%至20%的五个浓度下对蜂蜜进行测试。
本研究中使用的所有蜂蜜均抑制了13种细菌中的12种,只有粘质沙雷氏菌和白色念珠菌未被蜂蜜抑制。蜂蜜浓度<1%时几乎没有抗菌活性,5%时抑制作用最小。没有一种蜂蜜能够完全抑制细菌生长。虽然医用蜂蜜和麦卢卡蜂蜜总体活性最佳,但本地生产的蜂蜜对部分而非全部细菌具有同等的抑制活性。
非作为抗菌蜂蜜市售的其他蜂蜜可能具有同等的抗菌活性。这些新发现的抗菌蜂蜜可能会成为未来治疗用蜂蜜的宝贵来源。