Ancel David, Lefebvre Mathieu, Peyrin-Biroulet Laurent, Chone Laurence, Sido Andréa, Regent Denis, Bigard Marc-André
Service d'Hépato-Gastroentérologie, CHU Brabois, 54500 Vandoeuvre-les-Nancy, France.
Gastroenterol Clin Biol. 2005 Jun-Jul;29(6-7):743-5. doi: 10.1016/s0399-8320(05)82166-9.
The occurrence of pancreatic pseudocysts of the right hepatic lobe during acute biliary pancreatitis is a rare event. We report the unusual case of a 69-year-old woman who was hospitalised for biliary pancreatitis. The patient suffered from right hypochondrial pain. A CT-scan performed at day 12 showed pancreatic pseudocysts in the right hepatic lobe. A favorable outcome was obtained after percutaneous drainage. Most hepatic pseudocysts are described in the left hepatic lobe after alcoholic pancreatitis. Different hypotheses have been suggested to explain the extension of pancreatic pseudocysts in the liver, due to proteolytic effect of pancreatic enzymes that reach the lesser sac and then the liver either directly through the liver capsule, or indirectly through the hepatic hilum vessels, or the hepatic ligament. We suggest another reason for hepatic invasion: pancreatic enzymes could also cause liver damage, through the para - renal anterior space, often infiltrated during acute pancreatitis, reaching right hepatic lobe through area nuda.
急性胆源性胰腺炎期间右肝叶出现胰腺假性囊肿是一种罕见事件。我们报告了一例不同寻常的病例,一名69岁女性因胆源性胰腺炎住院。患者右上腹疼痛。第12天进行的CT扫描显示右肝叶有胰腺假性囊肿。经皮引流后获得了良好的结果。大多数肝假性囊肿是在酒精性胰腺炎后在左肝叶被描述的。由于胰腺酶的蛋白水解作用,有人提出了不同的假说来解释胰腺假性囊肿在肝脏中的扩展,这些酶通过小网膜囊,然后要么直接通过肝包膜,要么间接通过肝门血管或肝韧带到达肝脏。我们提出了肝侵犯的另一个原因:胰腺酶也可能通过肾旁前间隙导致肝损伤,急性胰腺炎期间该间隙常被浸润,通过裸区到达右肝叶。