Ginnelly Laura, Sculpher Mark, Bojke Chris, Roberts Ian, Wade Angie, Diguiseppi Carolyn
Centre for Health Economics, University of York, York, UK.
Eur J Public Health. 2005 Oct;15(5):448-53. doi: 10.1093/eurpub/cki146. Epub 2005 Sep 8.
In 2001, 486 deaths and 17,300 injuries occurred in domestic fires in the UK. Domestic fires represent a significant cost to the UK economy, with the value of property loss alone estimated at pounds 375 million in 1999. In 2001 in the US, there were 383 500 home fires, resulting in 3110 deaths, 15,200 injuries and dollar 5.5 billion in direct property damage.
A cluster RCT was conducted to determine whether a smoke alarm give-away program, directed to an inner-city UK population, is effective and cost-effective in reducing the risk of fire-related deaths/injuries. Forty areas were randomized to the give-away or control group. The number of injuries/deaths and the number of fires in each ward were collected prospectively. Cost-effectiveness analysis was undertaken to relate the number of deaths/injuries to resource use (damage, fire service, healthcare and give-away costs). Analytical methods were used which reflected the characteristics of the trial data including the cluster design of the trial and a large number of zero costs and effects.
The mean cost for a household in a give-away ward, including the cost of the program, was pounds 12.76, compared to pounds 10.74 for the control ward. The total mean number of deaths and injuries was greater in the intervention wards then the control wards, 6.45 and 5.17. When an injury/death avoided is valued at pounds 1000, a smoke alarm give-away has a probability of being cost effective of 0.15.
A smoke alarm give-away program, as administered in the trial, is unlikely to represent a cost-effective use of resources.
2001年,英国国内火灾导致486人死亡,17300人受伤。国内火灾给英国经济带来了巨大损失,仅1999年财产损失价值就估计达3.75亿英镑。2001年美国发生了383500起家庭火灾,造成3110人死亡,15200人受伤,直接财产损失达55亿美元。
进行了一项整群随机对照试验,以确定针对英国市中心人口的烟雾报警器赠送计划在降低火灾相关死亡/受伤风险方面是否有效且具有成本效益。40个区域被随机分为赠送组或对照组。前瞻性收集每个病房的受伤/死亡人数和火灾次数。进行成本效益分析,以将死亡/受伤人数与资源使用情况(损失、消防、医疗保健和赠送成本)相关联。使用的分析方法反映了试验数据的特征,包括试验的整群设计以及大量的零成本和零效果。
赠送病房中每户家庭的平均成本,包括该计划的成本,为12.76英镑,而对照病房为10.74英镑。干预病房的死亡和受伤总数高于对照病房,分别为6.45人和5.17人。当避免一次受伤/死亡的价值定为1000英镑时,烟雾报警器赠送计划具有成本效益的概率为0.15。
试验中实施的烟雾报警器赠送计划不太可能是资源的成本效益利用方式。