Koitschev A, Wolff A, Koitschev C, Preyer S, Ziebach R, Stern M
Univ.-HNO-Klinik Tübingen.
HNO. 2006 May;54(5):361-4, 366, 368. doi: 10.1007/s00106-005-1328-9.
Data on the prevalence of otorhinolaryngological (ORL) symptoms in patients with cystic fibrosis (CF) are limited. A standard annual examination would be useful for definition of risk factors and/or management alternatives for these symptoms.
Prospective observational study of an unselected group of CF patients.
Between 1997 and 2004, 123 CF patients were routinely examined. The examinations included nasal endoscopy and audiological evaluation.
All patients who were approached to take part in the study gave their consent and were extremely cooperative. In 40% of the patients nasal polyps were found endoscopically. In 22% rhinological surgery had already been performed. Of the 123 patients, 13 (12%) showed different grades of sensorineural hearing loss, and all of these patients had received aminoglycoside antibiotics.
CF patients demonstrate a high prevalence of ORL symptoms. Therefore, an annual standard examination would provide data for identifying potential risk factors and for optimizing the management of these symptoms in CF patients.
关于囊性纤维化(CF)患者耳鼻咽喉科(ORL)症状患病率的数据有限。标准的年度检查对于确定这些症状的危险因素和/或管理方案将是有用的。
对一组未经挑选的CF患者进行前瞻性观察研究。
1997年至2004年间,对123例CF患者进行了常规检查。检查包括鼻内镜检查和听力评估。
所有被邀请参加研究的患者均表示同意并极为配合。在内镜检查中发现40%的患者有鼻息肉。22%的患者已经接受了鼻科手术。在123例患者中,13例(12%)表现出不同程度的感音神经性听力损失,所有这些患者均接受过氨基糖苷类抗生素治疗。
CF患者的ORL症状患病率很高。因此,年度标准检查将为识别潜在危险因素和优化CF患者这些症状的管理提供数据。