Hunter Peter, Nielsen Poul
Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Physiology (Bethesda). 2005 Oct;20:316-25. doi: 10.1152/physiol.00022.2005.
Organ function (the heart beat for example) can only be understood through knowledge of molecular and cellular processes within the constraints of structure-function relations at the tissue level. A quantitative modeling framework that can deal with these multiscale issues is described here under the banner of the International Union of Physiological Sciences Physiome Project.
器官功能（例如心跳）只有在组织水平的结构 - 功能关系的约束下，通过了解分子和细胞过程才能被理解。在此，以国际生理科学联合会生理组项目的名义描述了一个能够处理这些多尺度问题的定量建模框架。
