NARCOMS注册库的验证：疲劳评估
Validation of the NARCOMS registry: fatigue assessment.
作者信息
Marrie Ruth Ann, Cutter Gary, Tyry Tuula, Hadjimichael Olympia, Campagnolo Denise, Vollmer Timothy
机构信息
Mellen Center for MS Treatment and Research, U10, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
出版信息
Mult Scler. 2005 Oct;11(5):583-4. doi: 10.1191/1352458505ms1216oa.
Participants in the North American Research Committee on Multiple Sclerosis (NARCOMS) Registry report disability using Performance Scales (PS), which assess eight domains. We aimed to validate the PS fatigue subscale (PSF) using the Fatigue Severity Scale (FSS) and the Modified Fatigue Impact Scale (MFIS) as external criteria. We measured correlations between the PSF and age, disease duration and PS subscales to assess construct validity. The PSF correlated strongly with the MFIS (r =0.72, P <0.0001) and FSS (r =0.75, P <0.0001). Correlations between the PSF and age, disease duration were low, indicating divergent validity. Correlations between the PSF and spasticity, sensory and mobility PS scales were moderate, indicating convergent validity. The PSF has adequate criterion and construct validity in MS.
北美多发性硬化症研究委员会（NARCOMS）登记处的参与者使用性能量表（PS）报告残疾情况，该量表评估八个领域。我们旨在使用疲劳严重程度量表（FSS）和改良疲劳影响量表（MFIS）作为外部标准来验证PS疲劳子量表（PSF）。我们测量了PSF与年龄、病程和PS子量表之间的相关性，以评估结构效度。PSF与MFIS（r = 0.72，P < 0.0001）和FSS（r = 0.75，P < 0.0001）密切相关。PSF与年龄、病程之间的相关性较低，表明具有区分效度。PSF与痉挛、感觉和运动PS量表之间的相关性中等，表明具有聚合效度。PSF在多发性硬化症中具有足够的标准效度和结构效度。
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