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J Clin Microbiol. 2005 Oct;43(10):5298-300. doi: 10.1128/JCM.43.10.5298-5300.2005.

2

Longitudinal analysis of cryptosporidium species-specific immunoglobulin G antibody responses in Peruvian children.秘鲁儿童隐孢子虫属特异性免疫球蛋白G抗体反应的纵向分析。

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Seroepidemiologic study of Cryptosporidium infection in children from rural communities of Anhui, China and Fortaleza, Brazil.中国安徽和巴西福塔雷萨农村社区儿童隐孢子虫感染的血清流行病学研究。

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Systemic antibody responses to the immunodominant p23 antigen and p23 polymorphisms in children with cryptosporidiosis in Bangladesh.孟加拉国隐孢子虫病患儿对免疫显性 p23 抗原和 p23 多态性的系统抗体反应。

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Serum antibody responses to polymorphic Cryptosporidium mucin antigen in Bangladeshi children with cryptosporidiosis.血清抗体对孟加拉国隐孢子虫病儿童中多态性隐孢子虫粘蛋白抗原的反应。

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Serum IgG response to Cryptosporidium immunodominant antigen gp15 and polymorphic antigen gp40 in children with cryptosporidiosis in South India.印度南部隐孢子虫病患儿对隐孢子虫免疫显性抗原gp15和多态性抗原gp40的血清IgG反应

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本文引用的文献

1

Effect of water and sanitation on childhood health in a poor Peruvian peri-urban community.水与卫生设施对秘鲁贫困城郊社区儿童健康的影响

Lancet. 2004 Jan 10;363(9403):112-8. doi: 10.1016/S0140-6736(03)15261-0.

2

Epidemiologic differences between cyclosporiasis and cryptosporidiosis in Peruvian children.秘鲁儿童中环孢子虫病和隐孢子虫病的流行病学差异

Emerg Infect Dis. 2002 Jun;8(6):581-5. doi: 10.3201/eid0806.01-0331.

3

Cryptosporidium parvum-specific antibody responses among children residing in Milwaukee during the 1993 waterborne outbreak.1993年水源性隐孢子虫病暴发期间，密尔沃基市儿童体内微小隐孢子虫特异性抗体反应。

J Infect Dis. 2001 May 1;183(9):1373-9. doi: 10.1086/319862. Epub 2001 Mar 29.

4

Enzyme immunoassay detection of antigen-specific immunoglobulin g antibodies in longitudinal serum samples from patients with cryptosporidiosis.酶免疫测定法检测隐孢子虫病患者纵向血清样本中的抗原特异性免疫球蛋白G抗体。

Clin Diagn Lab Immunol. 2001 Mar;8(2):415-23. doi: 10.1128/CDLI.8.2.415-423.2001.

5

Identification of 5 types of Cryptosporidium parasites in children in Lima, Peru.秘鲁利马儿童中5种隐孢子虫寄生虫的鉴定。

J Infect Dis. 2001 Feb 1;183(3):492-7. doi: 10.1086/318090. Epub 2000 Dec 20.

6

Detection by enzyme immunoassay of serum immunoglobulin G antibodies that recognize specific Cryptosporidium parvum antigens.通过酶免疫测定法检测血清中识别特定微小隐孢子虫抗原的免疫球蛋白G抗体。

J Clin Microbiol. 1999 May;37(5):1385-92. doi: 10.1128/JCM.37.5.1385-1392.1999.

7

The antibody response to 27-, 17-, and 15-kDa Cryptosporidium antigens following experimental infection in humans.人类实验性感染后对27 kDa、17 kDa和15 kDa隐孢子虫抗原的抗体反应。

J Infect Dis. 1998 Sep;178(3):827-33. doi: 10.1086/515377.

8

Comparison of PCR and microscopy for detection of Cryptosporidium parvum in human fecal specimens: clinical trial.聚合酶链反应（PCR）与显微镜检查法检测人粪便标本中小隐孢子虫的比较：临床试验

J Clin Microbiol. 1998 Apr;36(4):995-8. doi: 10.1128/JCM.36.4.995-998.1998.

9

Cryptosporidium parvum: intensity of infection and oocyst excretion patterns in healthy volunteers.微小隐孢子虫：健康志愿者的感染强度和卵囊排泄模式

J Infect Dis. 1996 Jan;173(1):232-6. doi: 10.1093/infdis/173.1.232.

10

Threshold of detection of Cryptosporidium oocysts in human stool specimens: evidence for low sensitivity of current diagnostic methods.人类粪便标本中隐孢子虫卵囊的检测阈值：当前诊断方法低敏感性的证据

J Clin Microbiol. 1991 Jul;29(7):1323-7. doi: 10.1128/jcm.29.7.1323-1327.1991.

秘鲁儿童中血清免疫球蛋白G水平变化作为隐孢子虫属感染标志物的研究

Changes in serum immunoglobulin G levels as a marker for Cryptosporidium sp. infection in Peruvian children.

作者信息

Priest Jeffrey W, Bern Caryn, Roberts Jacquelin M, Kwon James P, Lescano Andres G, Checkley William, Cabrera Lilia, Moss Delynn M, Arrowood Michael J, Sterling Charles R, Gilman Robert H, Lammie Patrick J

机构信息

Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.

出版信息

J Clin Microbiol. 2005 Oct;43(10):5298-300. doi: 10.1128/JCM.43.10.5298-5300.2005.

DOI:10.1128/JCM.43.10.5298-5300.2005

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1248452/

Abstract

In a retrospective analysis, we assessed the usefulness of two serologic enzyme-linked immunosorbent assays as epidemiologic tools for the detection of cryptosporidiosis episodes in children from a Peruvian community. The incidence rate determined by the serologic assay was higher than the rate determined by stool microscopy (0.77 versus 0.41 infection/child-year of surveillance).

摘要

在一项回顾性分析中，我们评估了两种血清学酶联免疫吸附测定法作为流行病学工具在检测秘鲁某社区儿童隐孢子虫病发病情况方面的效用。血清学测定法确定的发病率高于粪便显微镜检查确定的发病率（每儿童年监测感染率分别为0.77和0.41）。