Couto E, Chen B, Hemminki K
Department of Biosciences at Novum, Karolinska Institute, 141 57 Huddinge, Sweden.
Br J Cancer. 2005 Nov 28;93(11):1307-9. doi: 10.1038/sj.bjc.6602867.
Children whose twins have had leukaemia have a higher risk of contracting acute lymphoblastic leukaemia (ALL), confirming a prenatal origin of the disease. This association was not true when considering other types of affected first-degree relatives. Children whose fathers were diagnosed with testicular cancer have a higher risk of ALL.
双胞胎患有白血病的儿童患急性淋巴细胞白血病(ALL)的风险更高,这证实了该疾病的产前起源。当考虑其他类型的受影响一级亲属时,这种关联并不成立。父亲被诊断患有睾丸癌的儿童患ALL的风险更高。