Pierre-Kahn V, Tadayoni R, Haouchine B, Massin P, Gaudric A
Service d'Ophtalmologie, Hôpital Lariboisière 2, rue Ambroise Paré, 75475 Paris Cedex 10, France.
Br J Ophthalmol. 2005 Dec;89(12):1581-5. doi: 10.1136/bjo.2005.069815.
To compare the values measured for retinal macular thickness with the first and last generations of the optical coherence tomograph (OCT1 and Stratus OCT, Zeiss, Humphrey Division).
This was a cohort study. 59 eyes were examined: 17 had a normal macula and 42 had a diabetic macular oedema. In each eye, mean retinal thickness (RT) was measured automatically in the nine macular Early Treatment Diabetic Retinopathy Study areas and at the foveal centre, using OCT1 and Stratus OCT. The paired mean RT values for each area and the type and proportion of artefacts were compared.
Of the 590 automatic measurements, 505 had no artefact, either with OCT1 or Stratus OCT. The mean difference between the OCT1 and Stratus OCT measurements was 25 (SD 26.2) microm (p<0.0001). With Stratus OCT, RT values were significantly higher, by 8.1% (7.8%), than with OCT1. Artefacts were only observed in cases of diabetic macular oedema and were significantly more frequent with OCT1 than Stratus OCT (10.5% versus 4.4, p<0.0001).
The macular retinal thickness values measured with Stratus OCT were significantly higher than those measured with OCT1. Stratus OCT has the advantage of producing fewer artefacts than OCT1 in pathological cases.
比较使用第一代和最后一代光学相干断层扫描仪（OCT1和Stratus OCT，蔡司公司，汉弗莱事业部）测量的视网膜黄斑厚度值。
这是一项队列研究。对59只眼睛进行了检查：17只黄斑正常，42只患有糖尿病性黄斑水肿。使用OCT1和Stratus OCT，在每只眼睛的九个黄斑早期治疗糖尿病性视网膜病变研究区域以及黄斑中心自动测量平均视网膜厚度（RT）。比较每个区域的配对平均RT值以及伪像的类型和比例。
在590次自动测量中，505次测量无论是使用OCT1还是Stratus OCT均无伪像。OCT1和Stratus OCT测量值之间的平均差异为25（标准差26.2）微米（p<0.0001）。使用Stratus OCT时，RT值显著高于使用OCT1时，高出8.1%（7.8%）。仅在糖尿病性黄斑水肿病例中观察到伪像，且OCT1产生伪像的频率显著高于Stratus OCT（10.5%对4.4，p<0.0001）。
使用Stratus OCT测量的黄斑视网膜厚度值显著高于使用OCT1测量的值。在病理情况下，Stratus OCT具有比OCT1产生更少伪像的优势。
