Pinilla Isabel, Garcia-Martin Elena, Idoipe Miriam, Sancho Eva, Fuertes Isabel
Ophthalmology Department, Lozano Blesa University Hospital, c/ San Juan Bosco 15, 50009 Zaragoza, Spain.
J Ophthalmol. 2012;2012:107053. doi: 10.1155/2012/107053. Epub 2012 May 29.
Purpose. To compare the retinal nerve fiber layer (RNFL) measurements using two different ocular coherence tomography (OCT) devices: Cirrus Fourier domain OCT and Stratus time domain OCT. To analyze reproducibility of Fourier domain measurements in healthy subjects. Methods. One hundred and thirty-two eyes of 132 healthy subjects were scaned on the same day with both instruments, separated by 10 minutes from each other. Thickness of quadrant, average and the 12 different areas around the optic nerve were compared between Cirrus and Stratus. Repeatability, intraclass correlation coefficients (ICCs), and coefficients of variation (COVs) were calculated in RNFL measurements provided by Fourier domain device. Results. The average thickness in the optic cube was 95.50 μm using Cirrus and 97.85 μm using Stratus. Average thickness and temporal quadrant showed significant differences using Cirrus and Stratus methods. Reproducibility was better with Fourier domain OCT (mean COV of 4.54%) than with Stratus time-domain OCT (mean COV of 5.57%). Conclusions. Both scan options give reproducible RNFL thickness measurement, but there are differences between them. Measurements obtained using Fourier domain device show better reproducibility.
目的。比较使用两种不同的光学相干断层扫描（OCT）设备测量视网膜神经纤维层（RNFL）：Cirrus傅里叶域OCT和Stratus时域OCT。分析健康受试者傅里叶域测量的可重复性。方法。132名健康受试者的132只眼睛在同一天使用这两种仪器进行扫描，两次扫描间隔10分钟。比较Cirrus和Stratus之间象限、平均值以及视神经周围12个不同区域的厚度。计算傅里叶域设备提供的RNFL测量中的重复性、组内相关系数（ICC）和变异系数（COV）。结果。使用Cirrus时视盘立方体的平均厚度为95.50μm，使用Stratus时为97.85μm。使用Cirrus和Stratus方法时，平均厚度和颞侧象限显示出显著差异。傅里叶域OCT的可重复性（平均COV为4.54%）优于Stratus时域OCT（平均COV为5.57%）。结论。两种扫描方法均可获得可重复的RNFL厚度测量结果，但它们之间存在差异。使用傅里叶域设备获得的测量结果显示出更好的可重复性。
