严重急性呼吸综合征（SARS）患者中SARS冠状病毒特异性抗体的纵向分析。
Longitudinal analysis of Severe Acute Respiratory Syndrome (SARS) coronavirus-specific antibody in SARS patients.
作者信息
Chang Shan-Chwen, Wang Jann-Tay, Huang Li-Min, Chen Yee-Chun, Fang Chi-Tai, Sheng Wang-Huei, Wang Jiun-Ling, Yu Chong-Jen, Yang Pan-Chyr
机构信息
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
出版信息
Clin Diagn Lab Immunol. 2005 Dec;12(12):1455-7. doi: 10.1128/CDLI.12.12.1455-1457.2005.
Abstract
The serum antibodies to severe acute respiratory syndrome (SARS) coronavirus of 18 SARS patients were checked at 1 month and every 3 months after disease onset. All of them except one, who missed blood sampling at 1 month, tested positive for the immunoglobulin G (IgG) antibody at 1 month. Fifteen out of 17 tested positive for the IgM antibody at 1 month. The serum IgM antibody of most patients became undetectable within 6 months after the onset of SARS. The IgG antibody of all 17 patients, whose serum was checked 1 year after disease onset, remained positive.
摘要
对18例严重急性呼吸综合征（SARS）患者在发病后1个月及之后每3个月检测其针对SARS冠状病毒的血清抗体。除1例在1个月时错过采血的患者外，其余所有患者在1个月时免疫球蛋白G（IgG）抗体检测均为阳性。17例患者中有15例在1个月时IgM抗体检测为阳性。大多数患者的血清IgM抗体在SARS发病后6个月内无法检测到。在发病1年后对17例患者的血清进行检查，所有患者的IgG抗体仍为阳性。
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