Department of Chemical Engineering, Drexel University, Philadelphia, Pennsylvania 19104.
Appl Environ Microbiol. 1987 Jun;53(6):1232-5. doi: 10.1128/aem.53.6.1232-1235.1987.
The physiological response of Clostridium acetobutylicum to methyl and benzyl viologen was investigated. Viologen dyes at low concentrations (at levels of parts per million [micrograms per milliliter]) caused significant metabolic shifts. Altered electron flow appeared to direct carbon flow from acid to alcohol production accompanied by decreased hydrogen evolution. Reducing equivalents normally released as free hydrogen were directed toward formation of NADH which, in turn, resulted in increased alcohol production. In addition, it was shown that solvent production can take place at pH 6.3. Contrary to previous reports, butanol production appears to be independent of high levels of acetate-butyrate and glucose.
研究了丙酮丁醇梭菌对甲紫和联苯甲臜的生理反应。低浓度的联苯甲臜染料(百万分之几[微克/毫升]水平)引起了显著的代谢转变。改变的电子流似乎将碳流从酸引导到酒精生产,同时伴随着氢气的减少。正常作为自由氢释放的还原当量被引导形成 NADH,这反过来又导致酒精产量增加。此外,还表明溶剂生产可以在 pH 值为 6.3 时发生。与先前的报告相反,丁醇的生产似乎与高浓度的乙酸丁酯和葡萄糖无关。