产甲烷共培养物中丙酸分解代谢的提议途径。
A proposed pathway for catabolism of propionate in methanogenic cocultures.
机构信息
Department of Chemistry, Montana State University, Bozeman, Montana 59717.
出版信息
Appl Environ Microbiol. 1988 May;54(5):1300-1. doi: 10.1128/aem.54.5.1300-1301.1988.
Abstract
A metabolic pathway for the catabolism of propionate is proposed. This pathway incorporates a transcarboxylation reaction involving propionyl coenzyme A and oxaloacetate and a carboxylation of pyruvate to regenerate oxaloacetate. Data indicated that the proposed pathway is reversible. The proposed pathway and its apparent reversibility provide a reasonable explanation of observations obtained from metabolism of labeled substrate.
摘要
提出了丙酸分解代谢的代谢途径。该途径包括涉及丙酰辅酶 A 和草酰乙酸的转羧反应，以及丙酮酸的羧化作用以再生草酰乙酸。数据表明，所提出的途径是可逆的。所提出的途径及其明显的可逆性为标记底物代谢获得的观察结果提供了合理的解释。
相似文献
1
A proposed pathway for catabolism of propionate in methanogenic cocultures.产甲烷共培养物中丙酸分解代谢的提议途径。
Appl Environ Microbiol. 1988 May;54(5):1300-1. doi: 10.1128/aem.54.5.1300-1301.1988.
2
C nuclear magnetic resonance studies of propionate catabolism in methanogenic cocultures.C 核磁共振研究产甲烷共培养物中丙酸代谢。
Appl Environ Microbiol. 1987 Sep;53(9):2260-1. doi: 10.1128/aem.53.9.2260-2261.1987.
3
Inhibition of hepatic propionyl-CoA synthetase activity by organic acids. Reversal of propionate inhibition of pyruvate metabolism.有机酸对肝脏丙酰辅酶A合成酶活性的抑制作用。丙酸盐对丙酮酸代谢抑制作用的逆转。
Biochem Pharmacol. 1991;41(6-7):1015-23. doi: 10.1016/0006-2952(91)90209-n.
4
Carbon-13 nuclear magnetic resonance study of metabolism of propionate by Escherichia coli.大肠杆菌对丙酸盐代谢的碳-13核磁共振研究。
J Bacteriol. 1999 Jun;181(11):3562-70. doi: 10.1128/JB.181.11.3562-3570.1999.
5
Assessing the reversibility of the anaplerotic reactions of the propionyl-CoA pathway in heart and liver.评估丙酰辅酶A途径在心脏和肝脏中回补反应的可逆性。
J Biol Chem. 2003 Sep 12;278(37):34959-65. doi: 10.1074/jbc.M302013200. Epub 2003 Jun 24.
6
Reductive carboxylation of propionate to butyrate in methanogenic ecosystems.产甲烷生态系统中丙酸经还原羧化生成丁酸。
Appl Environ Microbiol. 1988 Feb;54(2):441-5. doi: 10.1128/aem.54.2.441-445.1988.
7
Mechanisms of growth inhibition by propionate and restoration of the growth by sodium bicarbonate or acetate in Rhodopseudomonas sphaeroides S.球形红假单胞菌S中丙酸盐抑制生长的机制以及碳酸氢钠或乙酸盐恢复生长的机制
J Biochem. 1985 Sep;98(3):819-24. doi: 10.1093/oxfordjournals.jbchem.a135340.
8
METABOLISM OF PROPIONATE BY SHEEP LIVER. INTERRELATIONS OF PROPIONATE AND GLUTAMATE IN AGED MITOCHONDRIA.绵羊肝脏中丙酸盐的代谢。衰老线粒体中丙酸盐与谷氨酸的相互关系。
Biochem J. 1965 May;95(2):431-6. doi: 10.1042/bj0950431.
9
Propionyl coenzyme A (propionyl-CoA) carboxylase in Haloferax mediterranei: Indispensability for propionyl-CoA assimilation and impacts on global metabolism.嗜盐嗜碱嗜盐栖热放线菌中的丙酰辅酶A（丙酰-CoA）羧化酶：丙酰辅酶A同化的不可或缺性及其对整体代谢的影响
Appl Environ Microbiol. 2015 Jan;81(2):794-804. doi: 10.1128/AEM.03167-14. Epub 2014 Nov 14.
10
Propionate formation in Rhodospirillum rubrum under anaerobic dark conditions.深红红螺菌在厌氧黑暗条件下丙酸酯的形成
Z Allg Mikrobiol. 1981;21(7):545-53. doi: 10.1002/jobm.3630210708.
引用本文的文献
1
Comprehensive Bioenergetic Evaluation of Microbial Pathway Variants in Syntrophic Propionate Oxidation.合成丙酸氧化中微生物途径变体的综合生物能量评估
mSystems. 2020 Dec 8;5(6):e00814-20. doi: 10.1128/mSystems.00814-20.
2
Pathway of propionate oxidation by a syntrophic culture of Smithella propionica and Methanospirillum hungatei.丙酸史密斯氏菌和亨氏甲烷螺菌的互营培养物对丙酸的氧化途径。
Appl Environ Microbiol. 2001 Apr;67(4):1800-4. doi: 10.1128/AEM.67.4.1800-1804.2001.
3
Metabolic interactions between anaerobic bacteria in methanogenic environments.产甲烷环境中厌氧细菌之间的代谢相互作用。
Antonie Van Leeuwenhoek. 1994;66(1-3):271-94. doi: 10.1007/BF00871644.
4
Effects of sulfate on lactate and C2-, C3- volatile fatty acid anaerobic degradation by a mixed microbial culture.硫酸盐对混合微生物培养物厌氧降解乳酸及C2-、C3-挥发性脂肪酸的影响。
Antonie Van Leeuwenhoek. 1990 Nov;58(4):241-8. doi: 10.1007/BF00399335.
本文引用的文献
1
C nuclear magnetic resonance studies of propionate catabolism in methanogenic cocultures.C 核磁共振研究产甲烷共培养物中丙酸代谢。
Appl Environ Microbiol. 1987 Sep;53(9):2260-1. doi: 10.1128/aem.53.9.2260-2261.1987.
2
Propionate exchange reactions in methanogenic ecosystems.产甲烷菌生态系统中的丙酸交换反应。
Appl Environ Microbiol. 1984 Oct;48(4):863-4. doi: 10.1128/aem.48.4.863-864.1984.
3
Pathways of propionate degradation by enriched methanogenic cultures.富甲烷菌培养物中丙酸的降解途径。
Appl Environ Microbiol. 1983 Apr;45(4):1411-4. doi: 10.1128/aem.45.4.1411-1414.1983.
4
THE METABOLISM OF PROPIONIC ACID.丙酸的代谢
Adv Enzymol Relat Subj Biochem. 1964;26:283-378. doi: 10.1002/9780470122716.ch7.
5
Stabilizing effect of acetate salts and HCO-3 in digestors receiving high levels of glucose.醋酸盐和HCO-3对接受高剂量葡萄糖的消化器的稳定作用。
Can J Microbiol. 1983 Oct;29(10):1405-11. doi: 10.1139/m83-216.
6
Synthesis and NMR spectra of 13C-labeled coenzyme A esters.
Anal Biochem. 1986 Aug 15;157(1):84-8. doi: 10.1016/0003-2697(86)90199-5.
Zotero 插件