诱导粘质沙雷氏菌产生黄色素。
Induction of Yellow Pigmentation in Serratia marcescens.
机构信息
Departament de Microbiologia i Parasitologia Sanitàries, Laboratori de Microbiologia, Facultat de Farmàcia, Universitat de Barcelona, 08028, Barcelona, Spain.
出版信息
Appl Environ Microbiol. 1988 Dec;54(12):3138-41. doi: 10.1128/aem.54.12.3138-3141.1988.
The appearance of yellow pigmentation in nonpigmented strains of Serratia sp. has been demonstrated to be due to the production of a muconic acid, 2-hydroxy-5-carboxymethylmuconic acid semialdehyde. The 3,4-dihydroxyphenylacetate 2,3-dioxygenase responsible for the synthesis of this muconic acid was induced in all strains tested. Another muconic acid, the beta-cis-cis-carboxymuconic acid, could also be synthesized from 3,4-dihydroxybenzoate, but this product was not colored. Mutants that were unable to grow on tyrosine and produced yellow pigment were isolated from nonpigmented strains. These mutants had properties similar to those of the yellow-pigmented strains. The ability to produce pigment may be more widespread among Serratia marcescens strains than is currently known.
黄色素在非色素变异沙雷氏菌中的出现，被证明是由于产生了粘康酸，即 2-羟基-5-羧甲基粘康酸半醛。所有受测试的菌株都诱导了合成这种粘康酸的 3,4-二羟基苯乙酸 2,3-加氧酶。另一种粘康酸，β-顺-顺-羧基粘康酸，也可以由 3,4-二羟基苯甲酸合成，但这种产物没有颜色。从非色素变异株中分离出不能在酪氨酸上生长并产生黄色色素的突变体。这些突变体具有与黄色色素变异株相似的特性。产生色素的能力可能比目前所知的在粘质沙雷氏菌菌株中更为普遍。
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