Baruch P, Filteau M J, Bouchard R H, Pourcher E, Vincent P, Jouvent R
Département de Psychiatrie, Hôpital de l'Enfant-Jésus, Québec, Canada.
J Psychiatry Neurosci. 1992 Jun;17(2):55-60.
The last decade has seen significant progress in the development and specific clinical application of selective psychotropes. The dimensional approach to clinical psychopharmacology views the behavioral targets of psychotropes as phenomena existing on a continuum and as components, in varying degrees, of most psychopathologies. The modern concept of dimension has been used in different contexts. In psychology it has a mathematical sense, whereas in biological psychiatry it is associated more with biological function. This paper reviews these two concepts and the recent models attempting to merge them into one. The heuristic value of the dimensional approach, as well as some of its pitfalls and new avenues of research, are discussed.
在过去十年中，选择性精神药物的研发及其特定的临床应用取得了重大进展。临床精神药理学的维度方法将精神药物的行为靶点视为存在于连续体上的现象，并且在不同程度上是大多数精神病理学的组成部分。现代维度概念已在不同背景下使用。在心理学中它具有数学意义，而在生物精神病学中它更多地与生物学功能相关联。本文回顾了这两个概念以及最近试图将它们合并为一个概念的模型。讨论了维度方法的启发式价值及其一些陷阱和新的研究途径。
