Banerjee Santanu, Chatterjee Manas, Chand Kailash
Military Hospital, Jodhpur, Rajasthan, India.
Indian J Dermatol Venereol Leprol. 2005 Nov-Dec;71(6):417-20. doi: 10.4103/0378-6323.18948.
Two patients with extramammary Paget's disease are being reported. The first case was a 60-year-old male who presented with gradually progressive pruritic ulcerated lesion over perianal region not responding to various topical medications. Dermatological examination revealed a large erythematous sharply marginated scaly plaque in the perianal region extending into the anal canal, covered with grayish crusts and shallow erosions. Skin biopsy from the lesion was suggestive of Paget's disease. The second patient, a 60-year-old male, with a three year long history, presented with similar lesions and findings. Skin biopsy in this case was also consistent with Paget's disease. These two cases of extramammary Paget's disease involving the perianal region are being reported because of their rarity and also to stress the fact that a high degree of suspicion is needed for the diagnosis of this uncommon disease entity.
报告了两例乳腺外佩吉特病患者。第一例是一名60岁男性，其肛周区域出现逐渐进展的瘙痒性溃疡性病变，对各种外用药物均无反应。皮肤科检查发现肛周区域有一个大的、边界清晰的红斑鳞屑斑块，延伸至肛管，覆盖着灰白色痂皮和浅糜烂面。病变部位的皮肤活检提示为佩吉特病。第二例患者是一名60岁男性，有三年病史，表现出类似的病变和检查结果。该病例的皮肤活检也符合佩吉特病。报告这两例累及肛周区域的乳腺外佩吉特病，是因为其罕见性，同时也强调对于诊断这种不常见疾病实体需要高度怀疑。
