Silpakit Chatchawan, Sirilerttrakul Suwanee, Jirajarus Manmana, Sirisinha Thitiya, Sirachainan Ekaphop, Ratanatharathorn Vorachai
Department of Psychiatry, Faculty of Medicine at Ramathibodi Hospital, 270 Rama VI Road, Rajathewee, Bangkok 10400, Thailand.
Qual Life Res. 2006 Feb;15(1):167-72. doi: 10.1007/s11136-005-0449-7.
The objective of this study was to assess the psychometric properties of the Thai version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) version 3.0. The questionnaire was completed by 310 cancer patients during their follow-up at 2 teaching hospital oncology clinics. About 70% of participants had advanced stage of cancer and 72% had been receiving chemotherapy. Cronbach's alpha coefficients of the six scales were above 0.7, except for cognitive and social function scales. All test-retest reliability coefficients were high. Multi trait scaling analysis showed that all item-scale correlation coefficients met the standards of convergent and discriminant validity. Most scales and items could discriminate between subgroups of patients with different clinical status assessed with the Eastern Cooperative Oncology Group (ECOG) scale. The results suggested that the EORTC QLQ-C30 and the Functional Assessment of Cancer Therapy - General (FACT-G) measured different aspects of quality of life and should be independently used. Testing psychometric properties of the EORTC QLQ-C30 in heterogeneous diagnostic group yield similar results as found in homogeneous group. These results support that the EORTC QLQ-C30 (version 3.0) has proven to be a reliable and valid measure of the quality of life in Thai patients with various types of cancer.
本研究的目的是评估欧洲癌症研究与治疗组织生活质量问卷（EORTC QLQ-C30）第3.0版泰语版本的心理测量特性。310名癌症患者在两家教学医院肿瘤门诊随访期间完成了该问卷。约70%的参与者处于癌症晚期，72%的患者正在接受化疗。除认知和社会功能量表外，六个量表的克朗巴哈α系数均高于0.7。所有重测信度系数都很高。多特质量表分析表明，所有项目-量表相关系数均符合收敛效度和区分效度的标准。大多数量表和项目能够区分根据东部肿瘤协作组（ECOG）量表评估的不同临床状态的患者亚组。结果表明，EORTC QLQ-C30和癌症治疗功能评估通用版（FACT-G）测量了生活质量的不同方面，应独立使用。在异质性诊断组中测试EORTC QLQ-C30的心理测量特性，得到的结果与同质性组相似。这些结果支持EORTC QLQ-C30（第3.0版）已被证明是泰国各类癌症患者生活质量的可靠有效测量工具。
