Baume N, Mahler N, Kamber M, Mangin P, Saugy M
Laboratoire Suisse d'Analyse du Dopage, Institut Universitaire de Médecine Légale, Département Universitaire de Médecine et Santé Communautaire, Lausanne, Switzerland.
Scand J Med Sci Sports. 2006 Feb;16(1):41-8. doi: 10.1111/j.1600-0838.2005.00442.x.
The purpose of this study was to analyze the composition of 103 dietary supplements bought on the internet. The supplements were dispatched in four different categories according to their announced contents [creatine, prohormones, "mental enhancers" and branched chain amino acids (BCAA)]. All the supplements were screened for the presence of stimulants and main anabolic steroids parent compounds. At the same time, the research was focused on the precursors and metabolites of testosterone and nandrolone. The study pointed out three products containing an anabolic steroid, metandienone, in a very high amount. The ingestion of such products induced a high quantity of metandienone metabolites in urines that would be considered as a positive antidoping test. The results have also shown that one creatine product and three "mental enhancers" contained traces of hormones or prohormones not claimed on the labels and 14 prohormone products contained substances other than those indicated by the manufacturer. The oral intake of the creatine product revealed the presence of the two main nandrolone metabolites (19-norandrosterone and 19-noretiocholanolone) in urine.
本研究的目的是分析在互联网上购买的103种膳食补充剂的成分。这些补充剂根据其宣称的成分[肌酸、促激素、“精神增强剂”和支链氨基酸(BCAA)]分为四类。所有补充剂都经过筛选,以检测其中是否含有兴奋剂和主要合成代谢类固醇母体化合物。同时,研究聚焦于睾酮和诺龙的前体及代谢物。该研究指出有三种产品含有大量的合成代谢类固醇美雄酮。摄入此类产品会导致尿液中出现大量美雄酮代谢物,这在反兴奋剂检测中会被视为阳性结果。结果还表明,有一种肌酸产品和三种“精神增强剂”含有标签上未宣称的微量激素或促激素,还有14种促激素产品含有制造商标注以外的物质。口服该肌酸产品后,尿液中检测出了两种主要的诺龙代谢物(19 - 去甲雄酮和19 - 去甲本胆烷醇酮)。