Grob Jean-Jacques, Gaudy-Marqueste Caroline
Université de la Méditerranée et Service de Dermatologie, Hôpital Ste Marguerite, Marseille, France.
Clin Rev Allergy Immunol. 2006 Feb;30(1):47-51. doi: 10.1385/CRIAI:30:1:047.
The common perspective of physicians on chronic urticaria (CU) refers to a benign disorder with no pain and no threat to function or life. Heath-related quality-of-life (HRQOL) tools have demonstrated the extent to which physicians underestimate the impact of this disorder. From the patient perspective, CU affects as many dimensions of the HRQOL as some life-threatening diseases or well-recognized disabling chronic skin disorders, such as psoriasis or atopic dermatitis. Pruritus as well as swelling and wheals triggered by unavoidable events, such as pressure or sweating, greatly contribute to HRQOL impairment. Recent trials have suggested that dermatology-specific HRQOL instruments could be more relevant than more objective severity scores when studying and comparing the benefit of various therapeutic strategies in chronic idiopathic urticaria.
医生对慢性荨麻疹（CU）的普遍看法是，它是一种良性疾病，不会引起疼痛，对功能或生命也没有威胁。健康相关生活质量（HRQOL）工具已经表明，医生在多大程度上低估了这种疾病的影响。从患者的角度来看，CU对HRQOL的影响程度与一些危及生命的疾病或公认的致残性慢性皮肤病（如银屑病或特应性皮炎）相当。瘙痒以及由不可避免的事件（如压力或出汗）引发的肿胀和风团，极大地导致了HRQOL受损。最近的试验表明，在研究和比较各种治疗策略对慢性特发性荨麻疹的益处时，特定于皮肤科的HRQOL工具可能比更客观的严重程度评分更具相关性。
