女性沙眼衣原体培养阳性时的宫颈炎和泌尿生殖系统症状

Cervicitis and genitourinary symptoms in women culture positive for Mycoplasma genitalium.

作者信息

Korte Jeffrey E, Baseman Joel B, Cagle Marianna P, Herrera Caleb, Piper Jeanna M, Holden Alan E C, Perdue Sondra T, Champion Jane D, Shain Rochelle N

机构信息

Department of Obstetrics and Gynecology, School of Medicine, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA.

出版信息

Am J Reprod Immunol. 2006 Apr;55(4):265-75. doi: 10.1111/j.1600-0897.2005.00359.x.

DOI:10.1111/j.1600-0897.2005.00359.x

PMID:16533338

Abstract

PROBLEM

Mycoplasma genitalium has been associated with male urethritis. We sought to relate M. genitalium to genitourinary signs and symptoms in women.

METHOD OF STUDY

We compared 26 culture-positive women (group 1), 257 additional polymerase chain reaction-positive women (group 2), and 107 negative control women. We used logistic regression to evaluate signs and symptoms, controlling for co-infections, pregnancy, age, and intervention group assignment.

RESULTS

Comparing group 1 with controls, we found significantly elevated odds ratios (ORs) for intermediate vaginal discharge (OR = 5.4; 95% confidence interval 1.01, 29.2) and action in response to discharge [3.9 (1.1, 13.5)]. Non-significant increases were observed for pathologic vaginal discharge [3.8 (0.78, 18.2)], pathologic dyspareunia [1.5 (0.25, 9.0)], vaginal odor [2.1 (0.75, 5.7)], and cervical mucopus [4.1 (0.74, 22.4)]. Group 2 results were similar, but showed no increase in cervical mucopus relative to controls.

CONCLUSION

Infection with M. genitalium in women is independently related to increased genitourinary symptomatology.

摘要

问题

生殖支原体与男性尿道炎有关。我们试图探究生殖支原体与女性泌尿生殖系统体征和症状之间的关系。

研究方法

我们比较了26名培养阳性的女性（第1组）、另外257名聚合酶链反应阳性的女性（第2组）以及107名阴性对照女性。我们使用逻辑回归来评估体征和症状，并对合并感染、妊娠、年龄和干预组分配进行控制。

结果

将第1组与对照组进行比较，我们发现中度白带增多（比值比=5.4；95%置信区间1.01，29.2）以及因白带增多而采取的行动[3.9（1.1，13.5）]的比值比显著升高。病理性白带增多[3.8（0.78，18.2）]、病理性性交困难[1.5（0.25，9.0）]、阴道异味[2.1（0.75，5.7）]和宫颈黏液脓性分泌物[4.1（0.74，22.4）]有非显著性增加。第2组的结果相似，但相对于对照组，宫颈黏液脓性分泌物没有增加。