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用细菌系统诱导和激发可使小鼠免受天花病毒感染，而循环干扰素则无法检测到。

Lack of detectable circulating interferon in mice protected against vaccinia virus by induction and elicitation with bacterial systems.

机构信息

Veterans Administration Hospital and Philadelphia General Hospital, Department of Community Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104.

出版信息

Infect Immun. 1973 Jan;7(1):117-8. doi: 10.1128/iai.7.1.117-118.1973.

DOI:10.1128/iai.7.1.117-118.1973
PMID:16558071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC422646/
Abstract

Mice which had been subjected to mycobacterial infection and specific elicitation were bled from the orbital sinus at the time the mice were challenged intravenously with vaccinia virus. Assays of the sera were negative for interferon. Sera of rabbits sensitized with staphylococci and elicited by Staphage Lysate also lacked detectable circulating interferon.

摘要

曾受到分枝杆菌感染和特定激发的小鼠，在静脉内接种牛痘病毒时，从眶窦采血。血清干扰素检测为阴性。用葡萄球菌致敏并经葡萄球菌噬菌体裂解物激发的兔血清也缺乏可检测到的循环干扰素。

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Lack of detectable circulating interferon in mice protected against vaccinia virus by induction and elicitation with bacterial systems.用细菌系统诱导和激发可使小鼠免受天花病毒感染，而循环干扰素则无法检测到。
Infect Immun. 1973 Jan;7(1):117-8. doi: 10.1128/iai.7.1.117-118.1973.
2
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引用本文的文献

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Protection of mice against vaccinia virus by bacterial infection and sustained stimulation with specific bacterial antigens.通过细菌感染和特定细菌抗原的持续刺激来保护小鼠免受痘苗病毒感染。
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Infect Immun. 1978 Jan;19(1):225-30. doi: 10.1128/iai.19.1.225-230.1978.

本文引用的文献

1
Relationship between dose size and dose interval of polyinosinic polycytidylic acid and interferon hyporesponsiveness in mice.小鼠中聚肌苷酸-聚胞苷酸的剂量大小与剂量间隔和干扰素低反应性之间的关系
Proc Soc Exp Biol Med. 1970 Nov;135(2):340-4. doi: 10.3181/00379727-135-35047.
2
Staphylococcidal capability of rabbit peritoneal macrophages in relation to infection and elicitation: induction and elicitation of activated macrophages.兔腹膜巨噬细胞的杀葡萄球菌能力与感染及激发的关系：活化巨噬细胞的诱导与激发
Infect Immun. 1972 May;5(5):763-8. doi: 10.1128/iai.5.5.763-768.1972.
3
Protection of mice against vaccinia virus by bacterial infection and sustained stimulation with specific bacterial antigens.通过细菌感染和特定细菌抗原的持续刺激来保护小鼠免受痘苗病毒感染。
Infect Immun. 1973 Jan;7(1):62-7. doi: 10.1128/iai.7.1.62-67.1973.