Garnacho-Montero Jose, Amaya-Villar Rosario
Intensive Care Unit, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Crit Care. 2006;10(2):132. doi: 10.1186/cc4860.
The clinical relevance of recovering Aspergillus species in intensive care unit patients is unknown. Diagnosis of invasive pulmonary aspergillosis is extremely difficult because there are no specific tests sensitive enough to detect it. The rapidly fatal prognosis of this infection without treatment justifies early antifungal therapy. A clinical algorithm may aid clinicians to manage critically ill patients from whose respiratory specimens Aspergillus spp. have been isolated. This new tool needs to be validated in a large cohort of patients before it can be recommended.
在重症监护病房患者中分离出曲霉菌属的临床相关性尚不清楚。侵袭性肺曲霉病的诊断极其困难，因为没有足够敏感的特异性检测方法来检测它。这种感染若不治疗，预后迅速致命，这证明了早期抗真菌治疗的合理性。一种临床算法可能有助于临床医生管理从其呼吸道标本中分离出曲霉菌属的重症患者。在推荐使用这个新工具之前，需要在大量患者队列中对其进行验证。
