Mitarai Keiichi, Gomi Fumi, Tano Yasuo
Department of Ophthalmology, Osaka University, Graduate School of Medicine, Room E7, 2-2 Yamadaoka Suita, Osaka, Japan.
Graefes Arch Clin Exp Ophthalmol. 2006 Nov;244(11):1415-20. doi: 10.1007/s00417-006-0277-7. Epub 2006 Apr 5.
The purpose of this study was to evaluate three-dimensional optical coherence tomographic findings at the leakage point on fluorescein angiography in central serous chorioretinopathy (CSC) with OCT-ophthalmoscope.
Twenty-seven eyes of 26 patients (23 men, three women; mean age, 50 years; range, 30-72) diagnosed with CSC were examined with OCT-ophthalmoscope, and transverse and longitudinal images were compared with fundus and fluorescein angiography findings.
Transverse images (C-scan) clearly showed serous retinal detachment in all eyes and irregular lesions in retinal pigment epithelium (RPE) in 26 of 27 eyes (96%). These results agreed with the location of lesions in areas of fluorescein dye leakage on fluorescein angiography. Longitudinal images (B-scan) of irregular RPE lesions in transverse images showed RPE detachment (PED) in 17 eyes (63%), small protrusion of the RPE layer in five eyes (19%), and rough RPE layer in four eyes (15%).
OCT-ophthalmoscope detects morphologic changes easily and noninvasively at the point of dye leakage in eyes with CSC.
本研究旨在使用光学相干断层扫描眼底镜（OCT-眼底镜）评估中心性浆液性脉络膜视网膜病变（CSC）患者荧光素血管造影渗漏点处的三维光学相干断层扫描结果。
对26例（23例男性，3例女性；平均年龄50岁；范围30 - 72岁）诊断为CSC的患者的27只眼进行OCT-眼底镜检查，并将横向和纵向图像与眼底及荧光素血管造影结果进行比较。
横向图像（C扫描）在所有眼中均清晰显示浆液性视网膜脱离，27只眼中26只眼（96%）视网膜色素上皮（RPE）有不规则病变。这些结果与荧光素血管造影中荧光素染料渗漏区域的病变位置一致。横向图像中不规则RPE病变的纵向图像（B扫描）显示17只眼（63%）有RPE脱离（PED），5只眼（19%）有RPE层小突起，4只眼（15%）有RPE层粗糙。
OCT-眼底镜能够轻松、无创地检测CSC患者眼部染料渗漏点处的形态学变化。
