Ziaee V, Razaei M, Ahmadinejad Z, Shaikh H, Yousefi R, Yarmohammadi L, Bozorgi F, Behjati M J
Islamic Medicine Research Centre, Tehran University of Medical Sciences, Iran.
Singapore Med J. 2006 May;47(5):409-14.
Ramadan is the holiest month in the Islamic calendar and Muslims fast during this month. We designed this study to evaluate the effect of Ramadan fasting on plasma lipids and lipoproteins.
This cohort study was performed during Ramadan in December 2002 (Islamic year 1423). The subjects were 81 students of Tehran University of Medical Sciences. We evaluated weight, body mass index (BMI), glucose, triglyceride (TG), cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), and very low density lipoprotein (VLDL), before and after Ramadan.
Body weight and BMI both decreased during Ramadan fasting in both genders. Glucose and HDL decreased and LDL increased significantly during fasting in Ramadan, but there was no significant change in total cholesterol, TG and VLDL. We did not find any association between TG, cholesterol, LDL, VLDL, HDL and the following variables: sex, body weight changes, and two or three instances of meals before Ramadan. Triglyceride level also increased in students with normal BMI while it decreased in overweight subjects.
This study indicated that Ramadan fasting led to a decrease in glucose and weight. Although there was a significant reduction in meal frequency, a significant increase in LDL and decrease in HDL was noted during Ramadan. It seems that the effect of Ramadan fasting on serum lipid levels may be closely related to the nutritional diet or biochemical response to starvation.
斋月是伊斯兰历中最神圣的月份，穆斯林在这个月禁食。我们设计了这项研究来评估斋月禁食对血浆脂质和脂蛋白的影响。
这项队列研究于2002年12月（伊斯兰历1423年）斋月期间进行。研究对象为德黑兰医科大学的81名学生。我们在斋月前后评估了体重、体重指数（BMI）、血糖、甘油三酯（TG）、胆固醇、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）和极低密度脂蛋白（VLDL）。
在斋月禁食期间，男女的体重和BMI均下降。斋月禁食期间，血糖和HDL下降，LDL显著升高，但总胆固醇、TG和VLDL无显著变化。我们未发现TG、胆固醇、LDL、VLDL、HDL与以下变量之间存在任何关联：性别、体重变化以及斋月前的两餐或三餐情况。BMI正常的学生甘油三酯水平升高，而超重学生的甘油三酯水平下降。
这项研究表明，斋月禁食导致血糖和体重下降。尽管进餐频率显著降低，但斋月期间LDL显著升高，HDL下降。看来斋月禁食对血脂水平的影响可能与营养饮食或对饥饿的生化反应密切相关。
