Gresser I, Tovey M G, Bourali-Maury C
J Gen Virol. 1975 Jun;27(3):395-8. doi: 10.1099/0022-1317-27-3-395.
Initiation of treatment with potent interferon preparations (6-4 x 10-6 units per dose) 4 days after intranasal inoculation of VSV (at a time when virus has already multiplied in the brains of most mice) resulted in a marked increase in mouse survival. In a series of 6 experiments only 11 to 18% of control mice survived whereas 52% of interferon treated mice survival. These results suggest the usefulness of exogenous interferon even when treatment is begun late in the course of an acute virus disease.
在用VSV经鼻接种4天后（此时病毒已在大多数小鼠的脑中增殖）开始用强效干扰素制剂进行治疗（每剂6 - 4×10⁻⁶单位），可使小鼠存活率显著提高。在一系列6个实验中，对照小鼠仅有11%至18%存活，而接受干扰素治疗的小鼠有52%存活。这些结果表明，即使在急性病毒病病程后期开始治疗，外源性干扰素也是有用的。
