Wiles Nicola J, Zammit Stanley, Bebbington Paul, Singleton Nicola, Meltzer Howard, Lewis Glyn
Academic Unit of Psychiatry, Department of Community Based Medicine, University of Bristol, The Grange, 1 Woodland Road, Bristol BS8 1AU, UK.
Br J Psychiatry. 2006 Jun;188:519-26. doi: 10.1192/bjp.bp.105.012179.
Scarce longitudinal data exist on the occurrence of psychotic symptoms in the general population.
To estimate the incidence of, and risk factors for, self-reported psychotic symptoms in Great Britain.
Data from the 18-month follow-up of a national survey were used. Incident cases were those who endorsed one or more items on the Psychosis Screening Questionnaire at follow-up, but not at baseline. The association between factors recorded at baseline and incident self-reported symptoms was examined.
At follow-up, 4.4% of the general population reported incident psychotic symptoms. Six factors were independently associated with incident symptoms: living in a rural area; having a small primary support group; more adverse life events; smoking tobacco; neurotic symptoms; and engaging in a harmful pattern of drinking.
A small but not insignificant percentage of the population of Great Britain reported incident psychotic symptoms over 18 months. The risk factors for psychotic symptoms showed some similarities with risk factors for schizophrenia, but there were also some striking differences. The relationship between such risk factors and the factors that perpetuate psychotic symptoms remains to be ascertained.
关于普通人群中精神病性症状发生情况的纵向数据稀缺。
估计英国自我报告的精神病性症状的发生率及危险因素。
使用来自一项全国性调查18个月随访的数据。新发病例是指在随访时认可精神病筛查问卷上一项或多项条目,但在基线时未认可的人。研究了基线记录的因素与新发自我报告症状之间的关联。
在随访时,4.4%的普通人群报告有新发精神病性症状。六个因素与新发症状独立相关:居住在农村地区;主要支持群体较小;有更多不良生活事件;吸烟;神经质症状;以及存在有害饮酒模式。
在18个月内,英国有一小部分但并非微不足道的人群报告有新发精神病性症状。精神病性症状的危险因素与精神分裂症的危险因素有一些相似之处,但也存在一些显著差异。这些危险因素与使精神病性症状持续存在的因素之间的关系仍有待确定。