Butz Arlene M, Tsoukleris Mona G, Donithan Michele, Hsu Van Doren, Zuckerman Ilene, Mudd Kim Elizabeth, Thompson Richard E, Rand Cindy, Bollinger Mary Elizabeth
Division of General Pediatrics, Department of Pulmonary and Critical Care, The Johns Hopkins University Medical Institutions, 600 N. Wolfe Street, Baltimore, MD 21287, USA.
Arch Pediatr Adolesc Med. 2006 Jun;160(6):622-8. doi: 10.1001/archpedi.160.6.622.
To determine the effectiveness of a home-based asthma education intervention in increasing appropriate nebulizer use and reducing symptom frequency, emergency department (ED) visits, and hospitalizations over 12 months.
A randomized clinical trial. Settings Pediatric primary care, pulmonary/allergy, and ED practices associated with the University of Maryland Medical System and The Johns Hopkins Hospital, Baltimore.
Children with persistent asthma, aged 2 to 9 years, with regular nebulizer use and an ED visit or hospitalization within the past 12 months. Children were randomized into the intervention (n = 110) or control (n = 111) group. Follow-up data were available for 95 intervention and 86 control children.
Home-based asthma education, including symptom recognition, home treatment of acute symptoms, appropriate asthma medication, and nebulizer practice.
Estimates of mean differences in asthma symptom frequency, number of ED visits and hospitalizations and appropriate quick relief, controller medication, and nebulizer practice over 12 months.
Of the 221 children, 181 (81.9%) completed the study. There were no significant differences in home nebulizer practice, asthma morbidity, ED visits, or hospitalizations between groups (P range, .11-.79). Although most children received appropriate nonurgent asthma care (mean, 2 visits per 6 months), more than one third of all children received at least 6 quick-relief medication prescriptions during 12 months, with no difference by group.
A nebulizer education intervention had no effect on asthma severity or health care use. Of concern is the high quick-relief and low controller medication use in young children with asthma seen nearly every 3 months for nonurgent care.
确定一项以家庭为基础的哮喘教育干预措施在增加雾化器合理使用以及在12个月内减少症状发作频率、急诊就诊次数和住院次数方面的效果。
一项随机临床试验。地点为与马里兰大学医学系统和巴尔的摩约翰霍普金斯医院相关的儿科初级保健、肺科/过敏科及急诊科。
年龄在2至9岁、持续使用雾化器且在过去12个月内有过急诊就诊或住院经历的持续性哮喘患儿。患儿被随机分为干预组(n = 110)或对照组(n = 111)。有95名干预组患儿和86名对照组患儿的随访数据。
以家庭为基础的哮喘教育,包括症状识别、急性症状的家庭治疗、合适的哮喘药物治疗以及雾化器使用练习。
12个月内哮喘症状发作频率、急诊就诊次数和住院次数的平均差异估计值,以及合理的快速缓解药物、控制药物使用情况和雾化器使用练习情况。
221名患儿中,181名(81.9%)完成了研究。两组在家庭雾化器使用、哮喘发病率、急诊就诊次数或住院次数方面无显著差异(P值范围为0.11 - 0.79)。尽管大多数患儿接受了适当的非紧急哮喘护理(平均每6个月就诊2次),但超过三分之一的患儿在12个月内至少接受了6次快速缓解药物处方,且两组之间无差异。
雾化器教育干预对哮喘严重程度或医疗保健利用无影响。令人担忧的是,患有哮喘的幼儿每近3个月因非紧急护理就诊时,快速缓解药物使用频繁而控制药物使用不足。