Quandt Sara A, Hernández-Valero María A, Grzywacz Joseph G, Hovey Joseph D, Gonzales Melissa, Arcury Thomas A
Division of Public Health Sciences, Dept. of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1063, USA.
Environ Health Perspect. 2006 Jun;114(6):943-52. doi: 10.1289/ehp.8529.
In this article we identify factors potentially associated with pesticide exposure among farmworkers, grade the evidence in the peer-reviewed literature for such associations, and propose a minimum set of measures necessary to understand farmworker risk for pesticide exposure. Data sources we reviewed included Medline, Science Citation Index, Social Science Citation Index, PsycINFO, and AGRICOLA databases. Data extraction was restricted to those articles that reported primary data collection and analysis published in 1990 or later. We read and summarized evidence for pesticide exposure associations. For data synthesis, articles were graded by type of evidence for association of risk factor with pesticide exposure as follows: 1 = association demonstrated in farmworkers; 2 = association demonstrated in nonfarmworker sample; 3 = plausible association proposed for farmworkers; or 4 = association plausible but not published for farmworkers. Of more than 80 studies we identified, only a third used environmental or biomarker evidence to document farmworker exposure to pesticides. Summaries of articles were compiled by level of evidence and presented in tabular form. A minimum list of data to be collected in farmworker pesticide studies was derived from these evidence tables. Despite ongoing concern about pesticide exposure of farmworkers and their families, relatively few studies have tried to test directly the association of behavioral and environmental factors with pesticide exposure in this population. Future studies should attempt to use similar behavioral, environmental, and psychosocial measures to build a body of evidence with which to better understand the risk factors for pesticide exposure among farmworkers.
在本文中,我们确定了与农场工人农药暴露潜在相关的因素,对同行评审文献中此类关联的证据进行了分级,并提出了了解农场工人农药暴露风险所需的最低限度措施。我们查阅的数据来源包括医学索引数据库(Medline)、科学引文索引(Science Citation Index)、社会科学引文索引(Social Science Citation Index)、心理学文摘数据库(PsycINFO)和农业联机存取数据库(AGRICOLA)。数据提取仅限于那些报告了1990年或之后发表的原始数据收集与分析的文章。我们阅读并总结了农药暴露关联的证据。为了进行数据综合分析,根据风险因素与农药暴露关联的证据类型对文章进行了如下分级:1 = 在农场工人中证实存在关联;2 = 在非农场工人样本中证实存在关联;3 = 针对农场工人提出的合理关联;或4 = 关联看似合理但未在农场工人中发表。在我们确定的80多项研究中,只有三分之一使用环境或生物标志物证据来记录农场工人接触农药的情况。文章摘要按证据水平进行汇编,并以表格形式呈现。农场工人农药研究中要收集的最低数据清单即来源于这些证据表。尽管人们一直关注农场工人及其家庭的农药暴露问题,但相对较少的研究试图直接检验行为和环境因素与该人群农药暴露之间的关联。未来的研究应尝试使用类似的行为、环境和社会心理测量方法来构建一批证据,以便更好地了解农场工人农药暴露的风险因素。