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Amplification and overexpression of the EGF receptor and c-erbB-2 proto-oncogenes in human stomach cancer.

作者信息

Lemoine N R, Jain S, Silvestre F, Lopes C, Hughes C M, McLelland E, Gullick W J, Filipe M I

机构信息

ICRF Molecular Oncology Group, Hammersmith Hospital, London, UK.

出版信息

Br J Cancer. 1991 Jul;64(1):79-83. doi: 10.1038/bjc.1991.243.

DOI:10.1038/bjc.1991.243
PMID:1677259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1977330/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37df/1977330/9e89d0e1e3d0/brjcancer00071-0087-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37df/1977330/ac127a8525dc/brjcancer00071-0087-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37df/1977330/9e89d0e1e3d0/brjcancer00071-0087-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37df/1977330/ac127a8525dc/brjcancer00071-0087-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37df/1977330/9e89d0e1e3d0/brjcancer00071-0087-b.jpg

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本文引用的文献

1
Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes.使用特异性克隆的cDNA探针检测α-和β-微管蛋白以及细胞质β-和γ-肌动蛋白基因的数量和进化保守性。
Cell. 1980 May;20(1):95-105. doi: 10.1016/0092-8674(80)90238-x.
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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells.人表皮生长因子受体cDNA序列及扩增基因在A431表皮样癌细胞中的异常表达。
Nature. 1984;309(5967):418-25. doi: 10.1038/309418a0.
3
A monoclonal antibody to the human epidermal growth factor receptor.
双特异性抗体为基础的免疫细胞衔接器及其在癌症免疫治疗中的新兴治疗靶点。
Int J Mol Sci. 2022 May 19;23(10):5686. doi: 10.3390/ijms23105686.
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Construction and analysis of lncRNA-associated ceRNA network identified potential prognostic biomarker in gastric cancer.lncRNA相关ceRNA网络的构建与分析鉴定出胃癌潜在的预后生物标志物。
Transl Cancer Res. 2019 Aug;8(4):1116-1128. doi: 10.21037/tcr.2019.06.32.
5
The Expression of p53, CD44, Ki-67, and HER-2/neu Markers in Gastric Cancer and Its Association with Histopathological Indicators: A Retrospective Study.p53、CD44、Ki-67 和 HER-2/neu 标志物在胃癌中的表达及其与组织病理学指标的关系：一项回顾性研究。
Asian Pac J Cancer Prev. 2020 Jun 1;21(6):1607-1614. doi: 10.31557/APJCP.2020.21.6.1607.
6
Association between ESR1, ESR2, HER2, UGT1A4, and UGT2B7 polymorphisms and breast Cancer in Jordan: a case-control study.ESR1、ESR2、HER2、UGT1A4 和 UGT2B7 多态性与约旦乳腺癌的关联：一项病例对照研究。
BMC Cancer. 2019 Dec 30;19(1):1257. doi: 10.1186/s12885-019-6490-7.
7
Poor survival after resection of early gastric cancer: extremes of survivorship analysis reveal distinct genomic profile.早期胃癌切除术后生存率低：生存极值分析揭示了不同的基因组特征。
Br J Surg. 2020 Jan;107(1):14-19. doi: 10.1002/bjs.11443. Epub 2019 Nov 25.
8
ErbB1 and ErbB3 co-over expression as a prognostic factor in gastric cancer.ErbB1 和 ErbB3 共表达作为胃癌的预后因素。
Biol Res. 2019 Jan 8;52(1):2. doi: 10.1186/s40659-018-0208-1.
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Sporadic amplification of the HER2/neu protooncogene in adenocarcinomas of various tissues.HER2/neu原癌基因在各种组织腺癌中的散发性扩增。
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Expression of the c-erbB-2 protein in normal and transformed cells.c-erbB-2蛋白在正常细胞和转化细胞中的表达。
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6
Genetic alterations of the c-erbB-2 oncogene occur frequently in tubular adenocarcinoma of the stomach and are often accompanied by amplification of the v-erbA homologue.c-erbB-2癌基因的基因改变在胃管状腺癌中频繁发生，且常伴有v-erbA同源物的扩增。
Oncogene. 1988 Mar;2(3):283-7.
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Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor.人类c-erb-B-2基因编码的蛋白质与表皮生长因子受体的相似性。
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Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas.
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9
Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancer.表皮生长因子受体状态作为乳腺癌早期复发和死亡的预测指标
Lancet. 1987 Jun 20;1(8547):1398-402. doi: 10.1016/s0140-6736(87)90593-9.
10
Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo.人腺癌中c-erbB-2癌基因在体内的扩增
Lancet. 1986 Apr 5;1(8484):765-7. doi: 10.1016/s0140-6736(86)91782-4.