Davido A, Patzak A, Dart T, Sadier M P, Méraud P, Masmoudi R, Sembach N, Cao T H
Département d'Accueil des Urgences, Hôpital Européen Georges Pompidou, (AP-HP); Faculté de Médecine René Descartes Paris 5, Paris, France.
Emerg Med J. 2006 Jul;23(7):515-8. doi: 10.1136/emj.2005.028290.
This study sought to determine the risk factors for short term mortality in the victims of the heat wave of August 2003 in France from among patients evaluated in our emergency department (ED). It was hypothesised that age, temperature, and some long term therapies and pre-existing pathologies were factors associated with short term mortality.
A retrospective analysis of a seven day period. Four experts decided blindly, in pairs, whether a patient had presented with a heat related problem. Inclusion criteria were: core temperature > or =38 degrees C and/or clinical signs of dehydration. Comparisons were made between the survivors and one month non-survivors for 57 different items. Short term mortality was defined as death in the ED or within the first month of the ED visit.
Of 841 patients attending the ED in the study period, 165 were included in the study, of which most were elderly women. Thirty one (18.8%) died within one month. Factors associated with short term mortality were: a greater degree of dependent living; more severe clinical condition on admission (higher temperature and heart rate, lower blood pressure, hypoxia, and altered mental status); higher values of blood glucose, troponin, and white blood cell count; lower values of serum protein and prothrombin levels; pre-existing ischaemic cardiomyopathy; pneumonia as associated infection; and previous psychotropic treatment. The total number of survivors at one year was 91.
Although this study is limited because of the small sample size, the results have helped determine factors useful for future identification of patients at greatest risk of death in order to implement a more efficient patient care protocol.
本研究旨在从我院急诊科评估的患者中确定2003年8月法国热浪受害者短期死亡的风险因素。研究假设年龄、温度、一些长期治疗方法和既往病症是与短期死亡相关的因素。
对为期七天的时间段进行回顾性分析。四位专家两两独立判断患者是否存在与热相关的问题。纳入标准为:核心体温≥38℃和/或脱水的临床体征。对57个不同项目的幸存者和1个月内非幸存者进行比较。短期死亡定义为在急诊科死亡或在急诊科就诊后的第一个月内死亡。
在研究期间到急诊科就诊的841例患者中,165例纳入研究,其中大多数为老年女性。31例(18.8%)在1个月内死亡。与短期死亡相关的因素包括:更高程度的依赖性生活;入院时临床状况更严重(体温和心率更高、血压更低、缺氧和精神状态改变);血糖、肌钙蛋白和白细胞计数更高;血清蛋白和凝血酶原水平更低;既往缺血性心肌病;肺炎作为相关感染;以及既往接受精神药物治疗。1年时幸存者总数为91例。
尽管本研究因样本量小而存在局限性,但研究结果有助于确定对未来识别死亡风险最高的患者有用的因素,以便实施更有效的患者护理方案。