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药用植物多糖的抗氧化活性。

Antioxidant activity of medicinal plant polysaccharides.

作者信息

Kardosová A, Machová E

机构信息

Institute of Chemistry, Slovak Academy of Sciences, 845 38 Bratislava, Slovakia.

出版信息

Fitoterapia. 2006 Jul;77(5):367-73. doi: 10.1016/j.fitote.2006.05.001. Epub 2006 May 24.

DOI:10.1016/j.fitote.2006.05.001
PMID:16797146
Abstract

Eleven polysaccharides have been isolated from the leaves of Arctium lappa var. herkules, Aloe barbadensis, Althaea officinalis var. robusta, Plantago lanceolata var. libor, aerial parts and roots of Rudbeckia fulgida var. sullivantii, stems of Mahonia aquifolium, and peach-tree (Prunus persica) gum exudates. The polysaccharides were investigated for their ability to inhibit peroxidation of soyabean lecithin liposomes by OH radicals. The highest inhibition was found with glucuronoxylans of A. officinalis var. robusta and P. lanceolata var. libor, aerial parts. Their antioxidant activity accounted for approximately 69% of the activity of the reference compound alpha-tocopherol. The activity of eight polysaccharides ranged from 20 to 45%, while the fructofuranan from P. lanceolata var. libor roots was practically inactive.

摘要

已从牛蒡变种赫库勒斯叶、库拉索芦荟、药蜀葵变种粗壮药蜀葵、窄叶车前变种利博尔、金光菊变种苏利文蒂的地上部分和根部、阔叶十大功劳茎以及桃树(桃)树胶渗出物中分离出11种多糖。研究了这些多糖抑制OH自由基对大豆卵磷脂脂质体过氧化作用的能力。发现药蜀葵变种粗壮药蜀葵和窄叶车前变种利博尔地上部分的葡糖醛酸木聚糖抑制作用最强。它们的抗氧化活性约占参考化合物α-生育酚活性的69%。8种多糖的活性在20%至45%之间,而窄叶车前变种利博尔根部的呋喃果糖聚糖几乎没有活性。

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