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法国重症监护病房无创通气使用的增加。

Increased use of noninvasive ventilation in French intensive care units.

作者信息

Demoule Alexandre, Girou Emmanuelle, Richard Jean-Christophe, Taillé Solenne, Brochard Laurent

机构信息

Service de Réanimation Médicale, AP-HP, Hôpital Henri Mondor, 51 av du Mal de Lattre de Tassigny, 94000, Créteil, France.

出版信息

Intensive Care Med. 2006 Nov;32(11):1747-55. doi: 10.1007/s00134-006-0229-z. Epub 2006 Jun 24.

Abstract

OBJECTIVES

A prospective survey of French intensive care units (ICUs) in 1997 showed moderate and variable use of noninvasive ventilation (NIV). This study examined changes in NIV use in French ICUs after the intervening 5years.

SETTINGS

Patients were enrolled in a prospective survey in 70 French ICUs.

METHODS

Three-week survey, with prospective inclusion of all patients requiring ventilatory support.

MEASUREMENTS AND RESULTS

Overall 1,076 patients received ventilatory support (55% of admissions). First-line NIV was significantly more common than 5years earlier, overall (23% vs. 16%) and especially in patients not intubated before ICU admission (52% vs. 35%). Reasons for respiratory failure were coma (33%), cardiogenic pulmonary edema (8%), acute-on-chronic respiratory failure (17%), and de novo respiratory failure (41%). Significant increases in NIV use were noted for acute-on-chronic respiratory failure (64% vs. 50%) and de novo respiratory failure (22% vs. 14%). Among patients given NIV, 38% subsequently required endotracheal intubation (not significantly different). Independent risk factors for NIV failure were high SAPS II and de novo respiratory failure, whereas factors associated with success were good NIV tolerance and high body mass index.

CONCLUSIONS

NIV use has significantly increased in French ICUs during the past 5years, and the success rate has remained unchanged. In patients not previously intubated, NIV is the leading first-line ventilation modality. The proportion of patients successfully treated with NIV increased significantly over the 5-year period (13% vs. 9% of all patients receiving ventilatory support).

摘要

目的

1997年对法国重症监护病房(ICU)进行的一项前瞻性调查显示,无创通气(NIV)的使用情况适中且存在差异。本研究调查了随后5年法国ICU中NIV使用情况的变化。

设置

对70家法国ICU的患者进行前瞻性调查。

方法

为期3周的调查,前瞻性纳入所有需要通气支持的患者。

测量与结果

共有1076例患者接受了通气支持(占入院患者的55%)。总体而言,一线NIV比5年前更为常见,总体比例为23% vs. 16%,尤其是在ICU入院前未插管的患者中(52% vs. 35%)。呼吸衰竭的原因包括昏迷(33%)、心源性肺水肿(8%)、慢性呼吸衰竭急性加重(17%)和新发呼吸衰竭(41%)。慢性呼吸衰竭急性加重(64% vs. 50%)和新发呼吸衰竭(22% vs. 14%)的NIV使用显著增加。在接受NIV的患者中,38%随后需要气管插管(无显著差异)。NIV失败的独立危险因素是高SAPS II评分和新发呼吸衰竭,而与成功相关的因素是良好的NIV耐受性和高体重指数。

结论

在过去5年中,法国ICU中NIV的使用显著增加,成功率保持不变。在以前未插管的患者中,NIV是主要的一线通气方式。在这5年期间,成功接受NIV治疗的患者比例显著增加(占所有接受通气支持患者的13% vs. 9%)。

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