Shinozaki Masae, Kanazawa Motoyori, Sagami Yasuhiro, Endo Yuka, Hongo Michio, Drossman Douglas A, Whitehead William E, Fukudo Shin
Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Seiryo, Aoba, Sendai, Japan.
J Gastroenterol. 2006 May;41(5):491-4. doi: 10.1007/s00535-006-1799-9.
Instruments for measuring the presence and severity of specific irritable bowel syndrome (IBS) symptoms, comparable to those used in Western countries, have been lacking in Japan. The aim of this study was to develop, validate, and confirm the reliability of the Japanese version of the Rome II modular questionnaire for IBS (RIIMQ-J) and the IBS severity index (IBSSI-J).
Forty-nine patients in the university hospital with chronic or recurrent abdominal pain and discomfort and/or altered bowel habits were enrolled. With Rome II criteria, 27 patients were diagnosed as having IBS, and the other 22 patients were evaluated as having other functional bowel disorders (FBDs). The English versions of RIIMQ and IBSSI were translated into Japanese. After back-translation and approval of the questionnaire, subjects completed both questionnaires twice within 14 days.
Cronbach's alpha of the RIIMQ-J was high (0.72). The sensitivity of RIIMQ-J for the diagnosis of IBS was also high (89%). The specificity of RIIMQ-J for denial of IBS among patients with other FBD was satisfactory (73%). The IBSSI-J showed high internal consistency (0.69) and reproducibility (intraclass correlation coefficient, 0.86, P < 0.001).
The RIIMQ-J and IBSSI-J are valid, reliable, and appropriate instruments for detecting and assessing the severity of IBS status in Japanese patients.
在日本，一直缺乏与西方国家所使用的类似的、用于测量特定肠易激综合征（IBS）症状的存在情况及严重程度的工具。本研究的目的是开发、验证并确认IBS的罗马II型模块化问卷日文版（RIIMQ-J）和IBS严重程度指数（IBSSI-J）的可靠性。
招募了49名在大学医院患有慢性或复发性腹痛、不适和/或排便习惯改变的患者。根据罗马II标准，27名患者被诊断为患有IBS，另外22名患者被评估为患有其他功能性肠病（FBD）。将RIIMQ和IBSSI的英文版翻译成日文。在回译并批准问卷后，受试者在14天内两次完成这两份问卷。
RIIMQ-J的Cronbach's alpha值较高（0.72）。RIIMQ-J对IBS诊断的敏感性也较高（89%）。RIIMQ-J在其他FBD患者中排除IBS的特异性令人满意（73%）。IBSSI-J显示出较高的内部一致性（0.69）和可重复性（组内相关系数，0.86，P < 0.001）。
RIIMQ-J和IBSSI-J是用于检测和评估日本患者IBS状态严重程度的有效、可靠且合适的工具。
