Carranza-Lira Sebastián, Hernandez Idun Berenice Villalobos
Instituto Mexicano del Seguro Social, México.
Prz Menopauzalny. 2014 Jun;13(3):169-73. doi: 10.5114/pm.2014.43819. Epub 2014 Jun 30.
To compare fibromyalgia prevalence in premenopausal and postmenopausal women and its relation to the climacteric symptoms.
Two hundred and nine women were studied, who attended the gynecology consultation at the hospital. They were divided in two groups: group I (premenopausal, n = 113) and group II (postmenopausal, n = 96). In all of them, climacteric symptoms and fibromyalgia diagnostic criteria were investigated; for the latter, the evaluations were done according to the 1990 and 2010 criteria of the American College of Rheumatology.
When groups I and II were compared, no differences were found in somatometry, medicament consumption and associated diseases. When analyzing the general group, the fibromyalgia prevalence was greater in the postmenopausal women. However, when comparing the groups according to climacteric symptoms, in group I, 29% of symptomatic women had fibromyalgia, while only 4% of asymptomatic ones (p < 0.002). In group II, 15.7% of symptomatic women, and 2.5% of asymptomatic ones had fibromyalgia (p < 0.02). In group I, the more common painful points were the lower back (45.5%), neck (35.7%), and upper back (32.1%). The more frequent symptoms were non-restful sleep (49%), followed by fatigue and cognitive symptoms (42% for each one). In group II, the more common painful points were the lower back (42%), neck (40%) and upper back (38.5%). The more frequent symptoms were fatigue (69.6%), cognitive symptoms (59.3%) and non-restful sleep (57%).
In premenopausal women, fibromyalgia was related to the presence of climacteric symptoms and in postmenopausal women - to their absence.
比较绝经前和绝经后女性纤维肌痛的患病率及其与更年期症状的关系。
对209名在医院妇科门诊就诊的女性进行研究。她们被分为两组:第一组(绝经前,n = 113)和第二组(绝经后,n = 96)。对所有研究对象调查更年期症状和纤维肌痛诊断标准;对于后者,根据美国风湿病学会1990年和2010年标准进行评估。
比较第一组和第二组时,在身体测量、药物使用和相关疾病方面未发现差异。分析总体人群时,绝经后女性纤维肌痛患病率更高。然而,根据更年期症状比较两组时,在第一组中,29%有症状的女性患有纤维肌痛,而无症状女性中只有4%(p < 0.002)。在第二组中,15.7%有症状的女性和2.5%无症状的女性患有纤维肌痛(p < 0.02)。在第一组中,较常见的疼痛部位是下背部(45.5%)、颈部(35.7%)和上背部(32.1%)。较常见的症状是睡眠不安(49%),其次是疲劳和认知症状(各占42%)。在第二组中,较常见的疼痛部位是下背部(42%)、颈部(40%)和上背部(38.5%)。较常见的症状是疲劳(69.6%)、认知症状(59.3%)和睡眠不安(57%)。
在绝经前女性中,纤维肌痛与更年期症状的存在有关,而在绝经后女性中——与更年期症状的不存在有关。