Wöber Christian, Holzhammer Julia, Zeitlhofer Josef, Wessely Peter, Wöber-Bingöl Ciçek
Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, A-1090, Vienna, Austria.
J Headache Pain. 2006 Sep;7(4):188-95. doi: 10.1007/s10194-006-0305-3. Epub 2006 Aug 11.
The objective was to examine potential trigger factors of migraine and tension-type headache (TTH) in clinic patients and in subjects from the population and to compare the patients' personal experience with their theoretical knowledge. A cross-sectional study was carried out in a headache centre. There were 120 subjects comprising 66 patients with migraine and 22 with TTH from a headache outpatient clinic and 32 persons with headache (migraine or TTH) from the population. A semistructured interview covering biographic data, lifestyle, medical history, headache characteristics and 25 potential trigger factors differentiating between the patients' personal experience and their theoretical knowledge was used. The most common trigger factors experienced by the patients were weather (82.5%), stress (66.7%), menstruation (51.4%) and relaxation after stress (50%). The vast majority of triggers occurred occasionally and not consistently. The patients experienced 8.9+/-4.3 trigger factors (range 0-20) and they knew 13.2+/-6.0 (range 1-27). The number of experienced triggers was smallest in the population group (p=0.002), whereas the number of triggers known did not differ in the three study groups. Comparing theoretical knowledge with personal experience showed the largest differences for oral contraceptives (65.0 vs. 14.7%, p<0.001), chocolate (61.7 vs. 14.3%, p>0.001) and cheese (52.5 vs. 8.4%, p<0.001). In conclusion, almost all trigger factors are experienced occasionally and not consistently by the majority of patients. Subjects from the population experience trigger factors less often than clinic patients. The difference between theoretical knowledge and personal experience is largest for oral contraceptives, chocolate and cheese.
目的是研究临床患者及普通人群中偏头痛和紧张型头痛（TTH）的潜在触发因素，并比较患者的个人体验与其理论知识。在一家头痛中心开展了一项横断面研究。共有120名受试者，其中包括66名来自头痛门诊的偏头痛患者、22名TTH患者，以及32名来自普通人群的头痛（偏头痛或TTH）患者。采用了一项半结构化访谈，内容涵盖个人资料、生活方式、病史、头痛特征以及25种潜在触发因素，以区分患者的个人体验和理论知识。患者经历的最常见触发因素为天气（82.5%）、压力（66.7%）、月经（51.4%）以及压力后的放松（50%）。绝大多数触发因素偶尔出现，并非持续发生。患者经历了8.9±4.3种触发因素（范围为0 - 20种），他们知晓13.2±6.0种（范围为1 - 27种）。在普通人群组中经历的触发因素数量最少（p = 0.002），而在三个研究组中知晓的触发因素数量并无差异。将理论知识与个人体验相比较，口服避孕药（65.0%对14.7%，p < 0.001）、巧克力（61.7%对14.3%，p > 0.001）和奶酪（52.5%对8.4%，p < 0.001）的差异最大。总之，几乎所有触发因素在大多数患者中都是偶尔出现，并非持续发生。普通人群中的受试者比临床患者经历触发因素的频率更低。口服避孕药、巧克力和奶酪在理论知识与个人体验之间的差异最大。
