Kim Kyo S, Nam Yu M
Department of Anesthesiology, Hanyang University Hospital, Seoul, Korea.
Anesth Analg. 2006 Sep;103(3):709-13. doi: 10.1213/01.ane.0000228864.74691.9f.
Acupuncture has been used to supplement opioid analgesics for postoperative pain control. We designed this double-blind, sham-controlled study to assess the effectiveness of capsicum plaster (PAS) at Zusanli (ST-36) acupoints on postoperative opioid analgesic requirement, side effects, and recovery profile.
Ninety women undergoing total abdominal hysterectomy were randomly assigned to 3 treatment regimens (n = 30 each): group Zusanli = PAS at Zusanli acupoints, group sham = PAS at the nonacupoints on the shoulders, and group control = placebo tape at Zusanli acupoints. The PAS was applied before induction of anesthesia and maintained for 8 h per day for 3 postoperative days.
The total amount of morphine administered in the first 24 h after the operation was significantly decreased in group Zusanli (31.5 +/- 6.8 mL) compared with groups control (44.3 +/- 10.1 mL) and sham (44.6 +/- 10.4 mL) (P < 0.01). The incidence of postoperative side effects and the use of rescue antiemetics during the 72 h after surgery were significantly reduced in group Zusanli compared with other groups (P < 0.01).
PAS at Zusanli points decreased the postoperative opioid requirement and opioid-related side effects of patients undergoing abdominal hysterectomy.
针刺已被用于辅助阿片类镇痛药以控制术后疼痛。我们设计了这项双盲、假对照研究，以评估在足三里（ST-36）穴位贴敷辣椒膏（PAS）对术后阿片类镇痛药需求、副作用及恢复情况的有效性。
90例行全腹子宫切除术的女性被随机分为3种治疗方案（每组n = 30）：足三里组 = 在足三里穴位贴敷PAS；假手术组 = 在肩部非穴位处贴敷PAS；对照组 = 在足三里穴位贴敷安慰剂胶布。PAS在麻醉诱导前应用，术后3天每天维持贴敷8小时。
与对照组（44.3±10.1 mL）和假手术组（44.6±10.4 mL）相比，足三里组术后24小时内吗啡的总用量显著减少（31.5±6.8 mL）（P < 0.01）。与其他组相比，足三里组术后72小时内副作用的发生率及补救性止吐药的使用显著减少（P < 0.01）。
在足三里穴位贴敷PAS可降低行腹式子宫切除术患者的术后阿片类药物需求及与阿片类药物相关的副作用。
