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赭曲霉毒素:全球视角

Ochratoxins: a global perspective.

作者信息

Bayman Paul, Baker James L

机构信息

Depto. de Biología, Universidad de Puerto Rico-Río Piedras, PO Box 23360, San Juan, PR, 00931, USA.

出版信息

Mycopathologia. 2006 Sep;162(3):215-23. doi: 10.1007/s11046-006-0055-4.

DOI:10.1007/s11046-006-0055-4
PMID:16944288
Abstract

Ochratoxins have been overshadowed by better-known mycotoxins, but they are gaining importance. Here we consider ochratoxins in the context of aflatoxins, which are better understood than ochratoxins on many levels. We review recent work on taxonomic distribution, contamination of commodities, biosynthesis, toxicity and regulatory aspects of ochratoxins. We focus on ochratoxins in coffee, since coffee is becoming a key commodity in ochratoxin research and regulation.

摘要

赭曲霉毒素一直被更为人熟知的霉菌毒素所掩盖,但它们正变得越来越重要。在此,我们将赭曲霉毒素置于黄曲霉毒素的背景下进行考量,黄曲霉毒素在许多层面上比赭曲霉毒素更易理解。我们综述了关于赭曲霉毒素的分类分布、商品污染、生物合成、毒性及监管方面的最新研究。我们重点关注咖啡中的赭曲霉毒素,因为咖啡正成为赭曲霉毒素研究与监管中的关键商品。

相似文献

1
Ochratoxins: a global perspective.赭曲霉毒素:全球视角
Mycopathologia. 2006 Sep;162(3):215-23. doi: 10.1007/s11046-006-0055-4.
2
Toxigenic fungi associated with processed (green) coffee beans (Coffea arabica L.).与加工(生)咖啡豆(阿拉伯咖啡)相关的产毒真菌。
Int J Food Microbiol. 2003 Aug 25;85(3):293-300. doi: 10.1016/s0168-1605(02)00539-1.
3
Ochratoxin a producing fungi from Spanish vineyards.
Adv Exp Med Biol. 2006;571:173-9. doi: 10.1007/0-387-28391-9_10.
4
Molecular characterization of ochratoxin A biosynthesis and producing fungi.赭曲霉毒素A生物合成及产毒真菌的分子特征
Adv Appl Microbiol. 2006;58:227-43.
5
Risk estimation for ochratoxin A in European countries.欧洲国家中赭曲霉毒素A的风险评估。
IARC Sci Publ. 1991(115):321-5.
6
Fungi producing ochratoxin in dried fruits.在干制水果中产生赭曲霉毒素的真菌。
Adv Exp Med Biol. 2006;571:181-8. doi: 10.1007/0-387-28391-9_11.
7
Worldwide regulations for ochratoxin A.全球赭曲霉毒素A法规。
IARC Sci Publ. 1991(115):331-6.
8
Production of ochratoxins A and B on country cured ham.乡村腌制火腿中赭曲霉毒素A和B的产生。
Appl Microbiol. 1973 Jul;26(1):27-30. doi: 10.1128/am.26.1.27-30.1973.
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Prevention of ochratoxin A in cereals in Europe.
Adv Exp Med Biol. 2006;571:317-42. doi: 10.1007/0-387-28391-9_21.
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[Ochratoxin A in foods for human consumption: review].[供人类食用食品中的赭曲霉毒素A:综述]
Nutr Hosp. 2011 Nov-Dec;26(6):1215-26. doi: 10.1590/S0212-16112011000600004.

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Molecular insights into ochratoxin A biodegradation.赭曲霉毒素A生物降解的分子见解。
Biol Futur. 2025 May 15. doi: 10.1007/s42977-025-00258-2.
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Occurrence and Fate Analysis of Mycotoxins in Maize During the Post-Harvest Period.玉米收获后期间真菌毒素的发生和命运分析。
Toxins (Basel). 2024 Oct 26;16(11):459. doi: 10.3390/toxins16110459.
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Ochratoxin A biodegradation by and statistical optimization of cultural variables.赭曲霉毒素A的生物降解及培养变量的统计优化

本文引用的文献

1
Prevention of ochratoxin A in cereals in Europe.
Adv Exp Med Biol. 2006;571:317-42. doi: 10.1007/0-387-28391-9_21.
2
Aflatoxin M(1) and ochratoxin A in a human milk bank in the city of São Paulo, Brazil.巴西圣保罗市一家母乳库中的黄曲霉毒素M1和赭曲霉毒素A。
Food Addit Contam. 2005 May;22(5):457-62. doi: 10.1080/02652030500110550.
3
Ochratoxin A: the continuing enigma.赭曲霉毒素A:持续的谜团。
Crit Rev Toxicol. 2005 Jan;35(1):33-60. doi: 10.1080/10408440590905948.
Food Sci Biotechnol. 2023 Sep 14;33(5):1221-1231. doi: 10.1007/s10068-023-01417-8. eCollection 2024 Apr.
4
Innovative approaches for mycotoxin detection in various food categories.各类食品中霉菌毒素检测的创新方法。
AMB Express. 2024 Jan 12;14(1):7. doi: 10.1186/s13568-024-01662-y.
5
Enzymatic degradation of ochratoxin A in the gastrointestinal tract of piglets.在仔猪胃肠道中对赭曲霉毒素 A 的酶促降解。
J Anim Sci. 2023 Jan 3;101. doi: 10.1093/jas/skad171.
6
From Grapes to Wine: Impact of the Vinification Process on Ochratoxin A Contamination.从葡萄到葡萄酒:酿造过程对赭曲霉毒素A污染的影响
Foods. 2023 Jan 6;12(2):260. doi: 10.3390/foods12020260.
7
Underreported Human Exposure to Mycotoxins: The Case of South Africa.未充分报告的人类霉菌毒素暴露情况:以南非为例。
Foods. 2022 Sep 5;11(17):2714. doi: 10.3390/foods11172714.
8
Combined Toxicity Evaluation of Ochratoxin A and Aflatoxin B1 on Kidney and Liver Injury, Immune Inflammation, and Gut Microbiota Alteration Through Pair-Feeding Pullet Model.通过对鸡的配对喂养模型评估赭曲霉毒素 A 和黄曲霉毒素 B1 对肝肾损伤、免疫炎症和肠道微生物群改变的联合毒性。
Front Immunol. 2022 Jul 29;13:920147. doi: 10.3389/fimmu.2022.920147. eCollection 2022.
9
Toolbox for the Extraction and Quantification of Ochratoxin A and Ochratoxin Alpha Applicable for Different Pig and Poultry Matrices.适用于不同猪和家禽基质的赭曲霉毒素 A 和赭曲霉毒素α提取和定量的工具箱。
Toxins (Basel). 2022 Jun 24;14(7):432. doi: 10.3390/toxins14070432.
10
Mycotoxins' Toxicological Mechanisms Involving Humans, Livestock and Their Associated Health Concerns: A Review.真菌毒素对人类、家畜及其相关健康问题的毒理学机制:综述。
Toxins (Basel). 2022 Feb 24;14(3):167. doi: 10.3390/toxins14030167.
4
Ochratoxin A producing Penicillium verrucosum isolates from cereals reveal large AFLP fingerprinting variability.从谷物中分离出的产赭曲霉毒素A的疣孢青霉菌株显示出较大的扩增片段长度多态性(AFLP)指纹图谱变异性。
J Appl Microbiol. 2005;98(3):684-92. doi: 10.1111/j.1365-2672.2004.02509.x.
5
Does human ochratoxin A aggravate proteinuria in patients with chronic renal disease?人源赭曲霉毒素A会加重慢性肾病患者的蛋白尿吗?
Ren Fail. 2004 May;26(3):311-6. doi: 10.1081/jdi-200026744.
6
An isolate of Aspergillus flavus used to reduce aflatoxin contamination in cottonseed has a defective polyketide synthase gene.一种用于减少棉籽中黄曲霉毒素污染的黄曲霉菌株具有一个有缺陷的聚酮合酶基因。
Appl Microbiol Biotechnol. 2004 Sep;65(4):473-8. doi: 10.1007/s00253-004-1670-y. Epub 2004 Jul 2.
7
Clustered pathway genes in aflatoxin biosynthesis.黄曲霉毒素生物合成中的成簇途径基因。
Appl Environ Microbiol. 2004 Mar;70(3):1253-62. doi: 10.1128/AEM.70.3.1253-1262.2004.
8
A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus.一种在赭曲霉中参与赭曲霉毒素A生物合成所需的聚酮合酶基因。
Microbiology (Reading). 2003 Dec;149(Pt 12):3485-3491. doi: 10.1099/mic.0.26619-0.
9
Mycotoxins.霉菌毒素
Clin Microbiol Rev. 2003 Jul;16(3):497-516. doi: 10.1128/CMR.16.3.497-516.2003.
10
On the safety of Aspergillus niger--a review.黑曲霉的安全性——综述
Appl Microbiol Biotechnol. 2002 Aug;59(4-5):426-35. doi: 10.1007/s00253-002-1032-6. Epub 2002 Jun 25.