晚期支气管癌的支气管镜冷冻治疗
Bronchoscopic cryotherapy for advanced bronchial carcinoma.
作者信息
Walsh D A, Maiwand M O, Nath A R, Lockwood P, Lloyd M H, Saab M
机构信息
Department of Thoracic Medicine, Harefield Hospital, Middlesex.
出版信息
Thorax. 1990 Jul;45(7):509-13. doi: 10.1136/thx.45.7.509.
A prospective study was carried out to assess the value of bronchoscopic cryotherapy for palliation of inoperable bronchial carcinoma with bronchial obstruction. Symptoms, lung function, and chest radiographic and bronchoscopic findings were recorded serially before and after 81 cryotherapy sessions in 33 consecutive patients. Most patients improved in terms of overall symptoms, stridor, and haemoptysis and they had an overall improvement in dyspnoea. Objective improvement in lung function was seen in 58% of patients and the changes in lung function correlated with symptoms. Bronchoscopic evidence of relief of bronchial obstruction was seen in 77% of patients and 24% showed improvement in degree of collapse on the radiograph. There were no important complications. These results compare favourably with the results in published series of patients having laser therapy. It is concluded that bronchoscopic cryotherapy is valuable for the palliation of inoperable bronchial carcinoma.
开展了一项前瞻性研究，以评估支气管镜冷冻疗法对无法手术切除且伴有支气管阻塞的支气管癌患者的姑息治疗价值。在33例连续患者接受81次冷冻治疗前后，连续记录症状、肺功能、胸部X光片及支气管镜检查结果。多数患者在总体症状、喘鸣及咯血方面有所改善，呼吸困难也整体得到改善。58%的患者肺功能有客观改善，且肺功能变化与症状相关。77%的患者支气管镜检查显示支气管阻塞得到缓解，24%的患者X光片显示肺不张程度有所改善。未出现重大并发症。这些结果与已发表的接受激光治疗患者系列的结果相比更具优势。得出结论，支气管镜冷冻疗法对无法手术切除的支气管癌的姑息治疗具有价值。
Zotero 插件