突尼斯一家大学医院中出现产VIM-4金属β-内酰胺酶、CTX-M-15超广谱β-内酰胺酶和CMY-4 AmpCβ-内酰胺酶的多重耐药肺炎克雷伯菌分离株。
Emergence of multidrug-resistant Klebsiella pneumoniae isolates producing VIM-4 metallo-beta-lactamase, CTX-M-15 extended-spectrum beta-lactamase, and CMY-4 AmpC beta-lactamase in a Tunisian university hospital.
作者信息
Ktari Sonia, Arlet Guillaume, Mnif Basma, Gautier Valérie, Mahjoubi Fouzia, Ben Jmeaa Mounir, Bouaziz Mounir, Hammami Adnane
机构信息
Laboratoire de Microbiologie, CHU Habib Bourguiba, Sfax, Tunisie.
出版信息
Antimicrob Agents Chemother. 2006 Dec;50(12):4198-201. doi: 10.1128/AAC.00663-06. Epub 2006 Oct 2.
Abstract
Klebsiella pneumoniae clinical isolates resistant to carbapenems were recovered from 11 patients in the hospital of Sfax, Tunisia. The isolates were closely related as shown by pulsed-field gel electrophoresis, and they produced VIM-4 metallo-enzyme, CTX-M-15 extended-spectrum beta-lactamase, and CMY-4 AmpC enzyme. The bla(VIM-4) gene is part of a class 1 integron.
摘要
从突尼斯斯法克斯医院的11名患者中分离出对碳青霉烯类耐药的肺炎克雷伯菌临床菌株。脉冲场凝胶电泳显示这些分离株密切相关，它们产生VIM-4金属酶、CTX-M-15超广谱β-内酰胺酶和CMY-4 AmpC酶。bla(VIM-4)基因是1类整合子的一部分。
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