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强直性脊柱炎患者附着点炎严重程度与临床及实验室参数之间的关系。

Relationship between the severity of enthesitis and clinical and laboratory parameters in patients with ankylosing spondylitis.

作者信息

Kaya Taciser, Bal Serpil, Gunaydin Rezzan

机构信息

Department of Physical Medicine and Rehabilitation, Izmir Research and Training Hospital, Izmir, Turkey.

出版信息

Rheumatol Int. 2007 Feb;27(4):323-7. doi: 10.1007/s00296-006-0218-0. Epub 2006 Sep 22.

Abstract

In this study, we evaluated the relationship between the severity of enthesitis and outcome of measurement indices, clinical and laboratory parameters in patients with ankylosing spondylitis (AS). Thirty-three patients who fulfilled the modified New York criteria for AS were included in this study. Patients were asked to record the severity of current pain, night pain and morning stiffness on a 10-cm visual analogue scale. Stoke Enthesitis Index (SEI) was used to measure the severity of enthesitis. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI) and Bath Ankylosing Spondylitis Metrology Index (BASMI) were calculated. SEI was correlated positively only with BASDAI (r = 0.370, P = 0.034). There was no relation between SEI and laboratory parameters (Erythrocyte Sedimentation Rate and C Reactive Protein). Our data suggest that using an enthesitis index such as SEI can be a valuable tool in the evaluation of disease activity in patients with AS. However, evaluation of enthesitis severity is based on information given by patient and should be combined with objective parameters such as spinal measurements when assessing disease activity.

摘要

在本研究中,我们评估了强直性脊柱炎(AS)患者的附着点炎严重程度与测量指标、临床及实验室参数结果之间的关系。本研究纳入了33例符合修订的纽约AS标准的患者。患者被要求在10厘米视觉模拟量表上记录当前疼痛、夜间疼痛及晨僵的严重程度。采用斯托克附着点炎指数(SEI)来测量附着点炎的严重程度。计算巴斯强直性脊柱炎疾病活动指数(BASDAI)、巴斯强直性脊柱炎功能指数(BASFI)和巴斯强直性脊柱炎计量指数(BASMI)。SEI仅与BASDAI呈正相关(r = 0.370,P = 0.034)。SEI与实验室参数(红细胞沉降率和C反应蛋白)之间无关联。我们的数据表明,使用诸如SEI这样的附着点炎指数可能是评估AS患者疾病活动度的一个有价值的工具。然而,附着点炎严重程度的评估基于患者提供的信息,在评估疾病活动度时应与诸如脊柱测量等客观参数相结合。

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