Department of Rheumatology, Ayachi Hospital, University Hospital of Rabat-Sale, 11000 Sale, Morocco.
Rheumatol Int. 2012 Mar;32(3):723-7. doi: 10.1007/s00296-010-1658-0. Epub 2010 Dec 15.
In this study, we evaluated the relationship between enthesitis and clinical, laboratory and quality-of-life parameters in ankylosing spondylitis (AS) in Moroccan patients. Seventy-six patients were included in this cross-sectional study according to the modified New York criteria for AS. All patients had enthesitis involvement. Clinical and biological parameters were evaluated. Enthesitis were assessed by two indices: Mander Enthesis Index (MEI) and Maastricht Ankylosing Spondylitis Enthesitis Score (MASES). Disease activity was evaluated by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Functional impact was assessed by the Bath Ankylosing Spondylitis Functional Index (BASFI). The quality of life was measured by the Short form-36 (SF-36). Severity of enthesitis was significantly correlated with disease activity, functional disability and degradation of quality of life. There was no relation between enthesitis indices and disease duration or laboratory parameters. The clinical assessment of enthesitis in AS is an important outcome measure, and enthesitis indices could be used to evaluate disease activity in patients with AS.
在这项研究中，我们评估了摩洛哥强直性脊柱炎（AS）患者附着点炎与临床、实验室和生活质量参数之间的关系。根据改良纽约 AS 标准，这项横断面研究纳入了 76 名患者。所有患者均存在附着点炎受累。评估了临床和生物学参数。附着点炎通过两个指标进行评估：Mander 附着点指数（MEI）和马斯特里赫特强直性脊柱炎附着点炎评分（MASES）。通过 Bath 强直性脊柱炎疾病活动指数（BASDAI）评估疾病活动度。通过 Bath 强直性脊柱炎功能指数（BASFI）评估功能障碍。通过 36 项简短健康调查问卷（SF-36）评估生活质量。附着点炎的严重程度与疾病活动度、功能障碍和生活质量下降显著相关。附着点炎指数与疾病持续时间或实验室参数之间无相关性。AS 附着点炎的临床评估是一个重要的结局指标，附着点炎指数可用于评估 AS 患者的疾病活动度。
