Probert M, Russell S M
J Clin Microbiol. 1975 Sep;2(3):157-61. doi: 10.1128/jcm.2.3.157-161.1975.
A single radial hemolysis assay for parainfluenza-3 virus antibody is described as a simple, sensitive, accurate, and precise alternative to hemagglutination inhibition and serum neutralization tests. A highly significant correlation exists between single radial hemolysis zone areas and hemagglutination inhibition titers of both serum and nasal secretion samples. Antibody conversions equivalent to as little as a twofold rise in hemagglutination inhibition titer are readily and reliably detected in sera and nasal secretions. Single radial hemolysis and hemagglutination inhibition activity was demonstrable in the immunoglobulin G fraction of a hyperimmune parainfluenza-3 virus antiserum.
一种用于检测副流感3型病毒抗体的单向放射状溶血试验被描述为一种简单、灵敏、准确且精密的方法，可替代血凝抑制试验和血清中和试验。血清和鼻分泌物样本的单向放射状溶血区面积与血凝抑制效价之间存在高度显著的相关性。在血清和鼻分泌物中能够轻松且可靠地检测到相当于血凝抑制效价仅两倍升高的抗体转化。在超免疫副流感3型病毒抗血清的免疫球蛋白G组分中可证明单向放射状溶血和血凝抑制活性。
