Jackson M L, Bassett K, Nirmalan P V, Sayre E C
Vision Rehabilitation Center, Massachusetts Eye and Ear Infirmary, Harvard Department of Ophthalmology, Boston, Massachusetts 02114, USA.
Br J Ophthalmol. 2007 Mar;91(3):296-8. doi: 10.1136/bjo.2006.104604. Epub 2006 Oct 11.
To examine the association of reported visual hallucinations and measured visual parameters in adult patients referred for low vision rehabilitation.
All patients (N = 225) referred to a low vision rehabilitation clinic for a calendar year were asked a standardised question about symptoms of formed visual hallucinations. Best corrected visual acuity and contrast sensitivity using the Pelli-Robson chart were measured. We conducted multiple logistic regression analysis of the association between visual hallucinations and visual parameters.
Of the total cohort, 78 (35%) reported visual hallucinations. Visual acuity and contrast sensitivity were considered in four quartiles. In multiple logistic regression controlling for contrast sensitivity, age, gender, report of depression and independence, measured acuity in each of the poorer three categories (compared to the best) was not associated with reported hallucinations. Contrast sensitivity in the three poorer quartiles (compared to the best) was strongly associated with the report of hallucinations (OR 4.1, CI 1.1, 15.9; OR 10.5, CI 2.6, 42.1; OR 28.1, CI 5.6, 140.9) after controlling for acuity, age, sex, depression and independence.
Lowest contrast sensitivity was the strongest predictor of reported hallucinations after adjusting for visual acuity.
研究转诊至低视力康复机构的成年患者中，所报告的视幻觉与所测量的视觉参数之间的关联。
询问了在一历年中转诊至一家低视力康复诊所的所有患者（N = 225）一个关于成形视幻觉症状的标准化问题。使用贝利-罗布森视力表测量了最佳矫正视力和对比敏感度。我们对视幻觉与视觉参数之间的关联进行了多项逻辑回归分析。
在整个队列中，78名（35%）报告有视幻觉。将视力和对比敏感度分为四个四分位数。在控制对比敏感度、年龄、性别、抑郁报告和独立性的多项逻辑回归分析中，较差的三个类别（与最佳类别相比）中的每一个类别所测量的视力与所报告的幻觉均无关联。在控制了视力、年龄、性别、抑郁和独立性后，较差的三个四分位数（与最佳四分位数相比）中的对比敏感度与幻觉报告密切相关（比值比4.1，可信区间1.1, 15.9；比值比10.5，可信区间2.6, 42.1；比值比28.1，可信区间5.6, 140.9）。
在调整视力后，最低对比敏感度是所报告幻觉的最强预测因素。
