基于DNA的机器。
DNA-based machines.
作者信息
Beissenhirtz Moritz K, Willner Itamar
机构信息
Institute of Chemistry and the Farkas Center for Light-Induced Processes, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
出版信息
Org Biomol Chem. 2006 Sep 21;4(18):3392-401. doi: 10.1039/b607033g. Epub 2006 Aug 4.
Nucleic acids include substantial information in their base sequence and their hybridization-complexation motifs. Recent research efforts attempt to utilize this biomolecular information to develop DNA nanostructures exhibiting machine-like functions. DNA nano-assemblies revealing tweezers, motor, and walker activities exemplify a few such machines. The DNA-based machines provide new components that act as sensitive sensors, transporters, or drug delivery systems.
核酸在其碱基序列和杂交复合基序中包含大量信息。最近的研究努力试图利用这种生物分子信息来开发具有类似机器功能的DNA纳米结构。展示镊子、马达和行走器活性的DNA纳米组装体就是这类机器的几个例子。基于DNA的机器提供了新的组件，可作为灵敏的传感器、转运体或药物递送系统。
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