Nyholt Dale R
Genetic Epidemiology Laboratory, QIMR 300 Herston Road, Brisbane, Queensland, 4006, Australia.
Bioinformatics. 2006 Dec 1;22(23):2960-1. doi: 10.1093/bioinformatics/btl518. Epub 2006 Oct 12.
ssSNPer is a novel user-friendly web interface that provides easy determination of the number and location of untested HapMap SNPs, in the region surrounding a tested HapMap SNP, which are statistically similar and would thus produce comparable and perhaps more significant association results. Identification of ssSNPs can have crucial implications for the interpretation of the initial association results and the design of follow-up studies.
ssSNPer是一个新颖且用户友好的网络界面,可轻松确定围绕一个已检测的HapMap单核苷酸多态性(SNP)区域中未检测的HapMap SNP的数量和位置,这些未检测的SNP在统计学上相似,因此可能会产生可比的、甚至可能更显著的关联结果。单倍型块内单核苷酸多态性(ssSNP)的识别对于初始关联结果的解释和后续研究的设计可能具有至关重要的意义。