Claessens Yann-Erick, Taupin Pierre, Kierzek Gérald, Pourriat Jean-Louis, Baud Michel, Ginsburg Christine, Jais Jean-Philippe, Jougla Eric, Riou Bruno, Dhainaut Jean-François, Landais Paul
Paris Descartes University, Faculty of Medicine, Assistance Publique--Hôpitaux de Paris, Department of Emergency Medicine, Hôpital Cochin, Paris Cedex 14, France.
Crit Care. 2006;10(6):R156. doi: 10.1186/cc5092.
A major issue raised by the public health consequences of a heat wave is the difficulty of detecting its direct consequences on patient outcome, particularly because of the delay in obtaining definitive mortality results. Since emergency department (ED) activity reflects the global increase of patients' health problems during this period, the profile of patients referred to EDs might be a basis to detect an excess mortality in the catchment area. Our objective was to develop a real-time surveillance model based on ED data to detect excessive heat-related mortality as early as possible.
A day-to-day composite indicator was built using simple and easily obtainable variables related to patients referred to the ED during the 2003 heat-wave period. The design involved a derivation and validation study based on a real-time surveillance system of two EDs at Cochin Hospital and Hôtel-Dieu Hospital, Paris, France. The participants were 99,976 adult patients registered from 1 May to 30 September during 2001, 2002 and 2003. Among these participants, 3,297, 3,580 and 3,851 patients were referred to the EDs from 3 August to 19 August for 2001, 2002 and 2003, respectively. Variables retained for the indicator were selected using the receiver operating characteristic curve methodology and polynomial regression.
The indicator was composed of only three variables: the percentage of patients older than 70 years, the percentage of patients with body temperature above 39 degrees C, and the percentage of patients admitted to or who died in the ED. The curve of the indicator with time appropriately fitted the overall mortality that occurred in the region of interest.
A composite and simple index based on real-time surveillance was developed according to the profile of patients who visited the ED. It appeared suitable for determining the overall mortality in the corresponding region submitted to the 2003 heat wave. This index should help early warning of excessive mortality and monitoring the efficacy of public health interventions.
热浪对公共卫生造成的后果引发的一个主要问题是,难以检测其对患者预后的直接影响,尤其是因为获得确切死亡率结果存在延迟。由于急诊科(ED)的活动反映了这一时期患者健康问题的总体增加,转诊至急诊科的患者特征可能是检测集水区超额死亡率的一个依据。我们的目标是基于急诊科数据开发一个实时监测模型,以便尽早检测与高温相关的超额死亡率。
使用与2003年热浪期间转诊至急诊科的患者相关的简单且易于获取的变量构建了一个每日综合指标。该设计涉及一项基于法国巴黎科钦医院和迪厄医院两个急诊科实时监测系统的推导和验证研究。参与者为2001年、2002年和2003年5月1日至9月30日登记的99976名成年患者。在这些参与者中,2001年、2002年和2003年分别有3297名、3580名和3851名患者在8月3日至8月19日转诊至急诊科。使用受试者工作特征曲线方法和多项式回归选择保留在指标中的变量。
该指标仅由三个变量组成:70岁以上患者的百分比、体温高于39摄氏度的患者的百分比以及在急诊科住院或死亡的患者的百分比。该指标随时间变化的曲线与感兴趣区域发生的总体死亡率适当拟合。
根据就诊于急诊科的患者特征开发了一个基于实时监测的综合且简单的指数。它似乎适用于确定2003年热浪影响的相应区域的总体死亡率。该指数应有助于对超额死亡率进行早期预警并监测公共卫生干预措施的效果。