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酒精性神经病变中的交感神经系统。一项临床与病理学研究。

The sympathetic nervous system in alcoholic neuropathy. A clinical and pathological study.

作者信息

Low P A, Walsh J C, Huang C Y, McLeod J G

出版信息

Brain. 1975 Sep;98(3):357-64. doi: 10.1093/brain/98.3.357.

DOI:10.1093/brain/98.3.357
PMID:171025
Abstract

Tests of autonomic function were performed on 12 subjects with alcoholic neuropathy. Abnormal sweat patterns occurred in 8/8 (100 per cent) and an abnormal Valsalva ratio in 2/9 (22 per cent). Postural hypotension and denervation hypersensitivity were absent in all patients examined. A quantitative assessment of baroreceptor function was made. The resting heart period, heart period range and mean gain of alcoholics were within the control range. Quantitative histological studies were performed on the greater splanchnic nerves removed at autopsy in 4 alcoholic subjects. The myelinated fibre density fell within the control range. The absence of significant disturbance of blood pressure control correlates well with the absence of pathology in the greater splanchnic nerve.

摘要

对12名酒精性神经病变患者进行了自主神经功能测试。8/8(100%)出现异常出汗模式,2/9(22%)出现异常瓦尔萨尔瓦比率。所有接受检查的患者均未出现体位性低血压和去神经超敏反应。对压力感受器功能进行了定量评估。酗酒者的静息心搏间期、心搏间期范围和平均增益均在对照范围内。对4名酗酒者尸检时切除的内脏大神经进行了定量组织学研究。有髓纤维密度在对照范围内。血压控制未出现明显紊乱与内脏大神经无病理学改变密切相关。

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